ArticleIn vivo (Athens, Greece)
Influence of Radiation Dose and Reconstruction Kernel on Fat Fraction Analysis in Dual-energy CT: A Phantom Study.
Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Usefulness of electron density imaging from dual-energy CT for detecting pulmonary thromboembolism in unenhanced CT.European radiology · 2026Article
- Evaluation of anemia in non-enhanced and contrast-enhanced dual-energy CT using electron density imaging.PloS one · 2026Article
- In vitro blood sample assessment: investigating correlation of laboratory hemoglobin and spectral properties of dual-energy CT measurements (ρ/Z).European radiology · 2024Article
- Pros and Cons of Dual-Energy CT Systems: "One Does Not Fit All".Tomography (Ann Arbor, Mich.) · 2023Review
- Assessment of Image Quality in Chest CT With Precision Matrix and Increased Framing Rate Using Single Source CT: A Phantom Study.In vivo (Athens, Greece)Article
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Authors and funding
6 authors.
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Abstract
BACKGROUND/
aimThe quantitative evaluation of fat tissue, mainly for the determination of liver steatosis, is possible by using dual-energy computed tomography. Different photon energy acquisitions allow for estimation of attenuation coefficients. The effect of variation in radiation doses and reconstruction kernels on fat fraction estimation was investigated. MATERIALS AND
methodsA six-probe-phantom with fat concentrations of 0%, 20%, 40%, 60%, 80%, and 100% were scanned in Sn140/100 kV with radiation doses ranging between 20 and 200 mAs before and after calibration. Images were reconstructed using iterative kernels (I26,Q30,I70).
resultsFat fractions measured in dual-energy computed tomography (DECT) were consistent with the 20%-stepwise varying actual concentrations. Variation in radiation dose resulted in 3.1% variation of fat fraction. Softer reconstruction kernel (I26) underestimated the fat fraction (-9.1%), while quantitative (Q30) and sharper kernel (I70) overestimated fat fraction (10,8% and 13,1, respectively).
conclusionThe fat fraction in DECT approaches the actual fat concentration when calibrated to the reconstruction kerneö. Variation of radiation dose caused an acceptable 3% variation.
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