Evidence map›Paper›PMID 34697136›Full record

ReviewIn vivo (Athens, Greece)

Adamantinoma: An Updated Review.

Dimitrios N Varvarousis, Georgios P Skandalakis, Alexandra Barbouti, Georgios Papathanakos, Panagiotis Filis, Kostas Tepelenis, Aikaterini Kitsouli, Panagiotis Kanavaros, Panagiotis Kitsoulis

Abstract readReview
In one paragraph

Review in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Adamantinoma: A SEER-based Epidemiological Analysis.Indian journal of surgical oncology · 2024
    Article
  8. Persistent Challenges: A Recurrent Adamantinoma - Case Report.Journal of orthopaedic case reports · 2024
    Article
  9. Article
  10. Tibial Adamantinoma: A Case Report from a Resource-Limited-Setting.International medical case reports journal · 2024
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Recurrent Adamantinoma With Fibrous Dysplasia-like Feature.Clinical pathology (Thousand Oaks, Ventura County, Calif.)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dimitrios N VarvarousisMedical School, University of Ioannina, Ioannina, Greece; dimvarvar@gmail.com.
Georgios P SkandalakisDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York City, NY, U.S.A.
Alexandra BarboutiDepartment of Anatomy - Histology-Embryology, University of Ioannina, Ioannina, Greece.
Georgios PapathanakosIntensive Care Unit, University Hospital of Ioannina, Ioannina, Greece.
Panagiotis FilisMedical School, University of Ioannina, Ioannina, Greece.
Kostas TepelenisDepartment of Surgery, University Hospital of Ioannina, Ioannina, Greece.
Aikaterini KitsouliUniversity of Ioannina, Ioannina, Greece.
Panagiotis KanavarosDepartment of Anatomy - Histology-Embryology, University of Ioannina, Ioannina, Greece.
Panagiotis KitsoulisDepartment of Anatomy - Histology-Embryology, University of Ioannina, Ioannina, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adamantinoma is a biphasic tumor, with a low potential for malignancy, characterized by clusters of epithelial cells surrounded by a relatively bland spindle-cell osteofibrous component. The aim of the present study was to review the updated data regarding epidemiology; pathogenesis; clinical presentation; radiological, histopathological and ultrastructural findings; and treatment options of adamantinoma. In X-ray, it is usually seen as an eccentric and sometimes central, lobular, lytic lesion with sclerotic margins of overlapping radiolucency, and a characteristic 'soap-bubble' appearance. Magnetic resonance imaging seems to be the most appropriate examination for differential diagnosis between adamantinoma and other skeletal tumors. Histologically, adamantinoma is identified as classic adamantinoma or osteofibrous-like adamantinoma. Classic adamantinoma is classified into four patterns of growth: Basaloid, tubular, spindle cell, and squamous. The preferable treatment of this tumor type is en bloc resection within wide operative margins, which may include suspicious regional lymph nodes, with limb reconstruction and limb salvage.

Indexed as

AdamantinomaBone NeoplasmsDiagnosis, DifferentialHumansMagnetic Resonance ImagingRadiographyTibiaAdamantinomadiagnosisreviewtreatment

Identifiers

PMID34697136
PMCPMC8627749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.