ArticleItalian journal of pediatrics2021
Prevention of recurrent respiratory infections : Inter-society Consensus.
Abstract readConsensus Statement
In one paragraph
Article in Italian journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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44citing papers in PubMed
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44 citing papers in PubMed.
- Novel Chewable Pleuran-Based Supplement Decreases Respiratory Tract Infections in Children: A Randomised Controlled Trial.Advances in therapy · 2025Trial
- Efficacy and tolerability of SEDIFLÙ in treating dry or productive cough in the pediatric population (SEPEDIA): A pilot, randomized, double-blind, placebo-controlled, multicenter clinical trial.Clinical pediatrics · 2024Trial
- Effects of Nasal Solution Incorporating Resveratrol and Carboxymethyl-Β-Glucan in Preschool Non-Atopic Children with Wheezing.Nutrients · 2024Trial
- Prevalence and risk factors of recurrent respiratory tract infections in preschool children: a systematic review and meta-analysis.Jornal de pediatria · 2026Review
- Endoplasmic reticulum stress-mediated disruption of mitochondrial homeostasis drives airway epithelial barrier fragility and enhances susceptibility to recurrent respiratory tract infections in children.Translational pediatrics · 2026Article
- The Impact of Adenotonsillectomy on Respiratory Tract Infections in Pediatric Patients: A Comparative Study Using a Korean Nationwide Population-Based Cohort.Journal of rhinology : official journal of the Korean Rhinologic Society · 2026Article
- The Role of Zinc in Pediatric Respiratory Infections: Evidence from Clinical Trials and Real-World Studies.Nutrients · 2026Review
- Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review).Molecular medicine reports · 2026Review
- Hypertonic thermal solutions as a putative strategy for respiratory biofilm disruption.Open medicine (Warsaw, Poland) · 2026Article
- Effects of Probiotics on Respiratory Tract Infections and Quality of Life in Children: A Large, Prospective, Community-Based Study.Patient preference and adherence · 2026Article
- An Italian multidisciplinary Delphi Consensus on new insights about the clinical relevance of Pidotimod.Multidisciplinary respiratory medicine · 2025Article
- Resveratrol as an Adjunct Antiviral Agent in Pediatric Viral Infections: A Review on Mechanistic Insights and Gut Microbiota Modulation.International journal of molecular sciences · 2025Review
- A narrative review and expert opinion on immunity-targeted approaches in the management of viral upper respiratory tract infections.NPJ primary care respiratory medicine · 2025Review
- Immune Development in Early Life (IDEaL) longitudinal cohort study protocol: Identifying biomarkers of vaccine responsiveness, respiratory infection, and asthma.The journal of allergy and clinical immunology. Global · 2025Article
- Thermal water inhalation for allergic rhinitis and recurrent respiratory infections: a narrative review of the evidence.Italian journal of pediatrics · 2025Review
- Pathogenic bacteria enriched in the oral microbiota might be associated with recurrent pulmonary infections in elderly individuals.Aging clinical and experimental research · 2025Article
- The prevalence of hearing impairment in infants and children with down syndrome a cross sectional study in a Tertiary Care Center.Scientific reports · 2025Article
- Secondary antibody deficiencies: what's around the corner?Frontiers in immunology · 2025Review
- Understanding and Managing Viral-Induced Wheezing in Children: The Role of Parental Knowledge.Journal of asthma and allergy · 2025Article
- Advancements related to probiotics for preventing and treating recurrent respiratory tract infections in children.Frontiers in pediatrics · 2025Review
Corrections and comments
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Authors and funding
49 authors.
Elena ChiappiniMeyer University Hospital, Department of Health Science, University of Florence, Florence, Italy. elena.chiappini@unifi.it.ORCID http://orcid.org/0000-0002-1476-4752
Francesca SantamariaDepartement of Translational Medical Sciences, Federico II University, Naples, Italy.
Gian Luigi MarsegliaDepartment of Pediatrics, University of Pavia IRCCS San Matteo foundation, Pavia, Italy.
Paola MarchisioFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Luisa GalliMeyer University Hospital, Department of Health Science, University of Florence, Florence, Italy.
Renato CutreraRespiratory Unit, Academic Pediatric Department, Pediatric Hospital Bambino Gesù IRCCS, Rome, Italy.
Maurizio de MartinoMeyer University Hospital, Department of Health Science, University of Florence, Florence, Italy.
Sara AntoniniMeyer University Hospital, Department of Health Science, University of Florence, Florence, Italy.
Paolo BecherucciFamily Pediatrician, Local Health Unit, Lastra a Signa, Florence, Italy.
Paolo BiasciFamily Pediatrician, Local Health Unit, Livorno, Italy.
Barbara BortoneMeyer University Hospital, Department of Health Science, University of Florence, Florence, Italy.
Sergio BotteroAirway Surgery Unit, Department of Pediatric Surgery, Bambino Gesù Children's Hospital, Rome, Italy.
Valeria CaldarelliDepartment of Obstetrics Gynaecology and Pediatrics, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Fabio CardinaleDepartment of Pediatrics, Pediatric Hospital Giovanni XXIII, University of Bari, Bari, Italy.
Guido Castelli GattinaraInstitute of child health, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
Martina CiarciàMeyer University Hospital, Department of Health Science, University of Florence, Florence, Italy.
Daniele CiofiMeyer University Hospital, Department of Health Science, University of Florence, Florence, Italy.
Sofia D'EliosDepartment of Clinical and Experimental Medicine, Section of Paediatrics, University of Pisa, Pisa, Italy.
Giuseppe Di MauroPediatric Primary Care, National Pediatric Health Care System, Caserta, Italy.
Mattia DoriaFamily Pediatrician, Local Health Unit, Chioggia, Venice, Italy.
Luciana IndinnimeoPediatric Department "Sapienza", University of Rome, Policlinico Umberto I, Rome, Italy.
Andrea Lo VecchioDepartement of Translational Medical Sciences, Federico II University, Naples, Italy.
Francesco MacrìDepartment of Pediatrics "Sapienza", University of Rome, Rome, Italy.
Roberto MattinaDepartment of Biomedical, Surgical, and Odontoiatric Sciences, Università degli Studi di Milano, Milan, Italy.
Vito Leonardo MinielloDepartment of Paediatrics, Paediatric Hospital Giovanni XXIII, Bari, Italy.
Michele Miraglia Del GiudiceDepartment of Woman and Child and General and Specialized Surgery, University of Campania Luigi Vanvitelli, Naples, Italy.
Guido MorbinFamily Pediatrician, Local Health Unit, Trento, Italy.
Marco Antonio MotisiMeyer University Hospital, Department of Health Science, University of Florence, Florence, Italy.
Andrea NovelliMeyer University Hospital, Department of Health Science, University of Florence, Florence, Italy.
Anna Teresa PalamaraDepartment of Public Health and Infectious Diseases, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, Italy.
Maria Laura PanattaDepartment of Otorhinolaryngology, IRCCS Bambino Gesù Pediatric Hospital, Rome, Italy.
Angela PasinatoFamily Pediatrician, Local Health Unit, Torri di Quartesolo, Vicenza, Italy.
Diego PeroniDepartment of Clinical and Experimental Medicine, Section of Paediatrics, University of Pisa, Pisa, Italy.
Katia PerruccioPediatric Oncology Hematology, Santa Maria della Misericordia Hospital, Perugia, Italy.
Giorgio PiacentiniDepartment of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Pediatric Clinic, University of Verona, Verona, Italy.
Massimo PifferiDepartment of Pediatrics Pulmonology and Allergology Section University Hospital of Pisa, Pisa, Italy.
Lorenzo PignataroFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Emanuela SitziaDepartment of Otorhinolaryngology, IRCCS Bambino Gesù Pediatric Hospital, Rome, Italy.
Chiara TersigniMeyer University Hospital, Department of Health Science, University of Florence, Florence, Italy.
Sara TorrettaFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Irene TrambustiDepartment of Clinical and Experimental Medicine, Section of Paediatrics, University of Pisa, Pisa, Italy.
Giulia TrippellaMeyer University Hospital, Department of Health Science, University of Florence, Florence, Italy.
Diletta ValentiniDepartment of Pediatric and Infectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Sandro ValentiniFamily Pediatrician, Local Health Unit, Colle Val d'Elsa, Siena, Italy.
Attilio VarricchioDepartment of Otolaryngology, Ospedale San Gennaro, Naples, Italy.
Maria Carmen VergaFamily Pediatrician, Local Health Unit Salerno, Vietri sul Mare, Salerno, Italy.
Claudio ViciniDepartment of Head-Neck Surgery, Otolaryngology, Head-Neck and Oral Surgery Unit, Morgagni Pierantoni Hospital, Forlì, Italy.
Marco ZeccaPediatric Hematology-Oncology, IRCCS Policlinico San Matteo, Pavia, Italy.
Alberto VillaniDepartment of Pediatric and Infectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recurrent respiratory infections (RRIs) are a common clinical condition in children, in fact about 25% of children under 1 year and 6% of children during the first 6 years of life have RRIs. In most cases, infections occur with mild clinical manifestations and the frequency of episodes tends to decrease over time with a complete resolution by 12 years of age. However, RRIs significantly reduce child and family quality of life and lead to significant medical and social costs.Despite the importance of this condition, there is currently no agreed definition of the term RRIs in the literature, especially concerning the frequency and type of infectious episodes to be considered. The aim of this consensus document is to propose an updated definition and provide recommendations with the intent of guiding the physician in the complex process of diagnosis, management and prevention of RRIs.
Indexed as
AdenoidectomyAdjuvants, ImmunologicAdministration, IntranasalAlgorithmsAntibiotic ProphylaxisAntioxidantsChildComplementary TherapiesHumansHyaluronic AcidInfluenza VaccinesPneumococcal VaccinesPrebioticsProbioticsPyrrolidonecarboxylic AcidRecurrenceAdjuvants, ImmunologicAntioxidantsHyaluronic AcidInfluenza VaccinespidotimodPneumococcal VaccinesPrebioticsPyrrolidonecarboxylic AcidResveratrolThiazolidinesVitaminsChildrenImmune systemPreventionRecurrent respiratory infections
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