Evidence map›Paper›PMID 34696623›Full record

ArticleCartilage2021

Retreatment with Hyaluronic Acid Viscosupplementation in Knee Osteoarthritis: Agreement between EUROVISCO Guidelines and Current Medical Practice.

Yves Henrotin, Cedric Tits, Jérôme Paul, Pierre Gramme, Thibault Helleputte, Alberto Migliore, Pascal Richette, Xavier Chevalier, Jordi Monfort, Demirhan Diracoglu and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Cartilage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 7 countries.

Yves HenrotinMusculoskeletal Innovative Research Lab, Arthropole Liège, Center for Interdisciplinary Research on Medicines, Institute of Pathology, University of Liège, Liège, Belgium.ORCID 0000-0003-1073-449X
Cedric TitsDNAlytics, Louvain-la-Neuve, Belgium.
Jérôme PaulDNAlytics, Louvain-la-Neuve, Belgium.
Pierre GrammeDNAlytics, Louvain-la-Neuve, Belgium.
Thibault HelleputteDNAlytics, Louvain-la-Neuve, Belgium.
Alberto MiglioreU.O.S. of Rheumatology, Ospedale San Pietro Fatebenefratelli, Rome, Italy.
Pascal RichetteUniversité Paris Diderot, UFR médicale, Hôpital Lariboisière, Paris, France.
Xavier ChevalierDepartment of Rheumatology, Hôpital Henri-Mondor, Assistance Publique-Hôpitaux de Paris, Créteil, France.
Jordi MonfortServei de Reumatologia, Hospital del Mar, Barcelona, Spain.
Demirhan DiracogluDepartment of Physical Medicine and Rehabilitation, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Hervé BardCabinet Medical Vaudoyer, Paris, France.
Jörg JeroschDepartment of Orthopedic, Johanna Etienne Hospital, Neuss, Germany.
Dominique BaronCentre de Réadaptation Fonctionnelle de Lannion-Trestel, Trévou-Tréguignec, France.
Raman RaghuAcademic Department of Orthopaedics, Hull and East Yorkshire NHS Trust Castle Hill Hospital, Cottingham, UK.
Thierry ConrozierHospital North Franche-Comté, Trévenans, France.
Assistance Publique – Hôpitaux de Paris · FRCastle Hill Hospital · GBCentre Hospitalier Lannion Trestel · FRHospital Del Mar · ESIstanbul University · TRJohanna-Etienne-Krankenhaus · DEOspedale San Pietro Fatebenefratelli · ITUniversité Paris Cité · FRUniversity of Liège · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis work studied if and how current clinical practice agrees with European Viscosupplementation Consensus Group (EUROVISCO) recommendations and how this agreement might be different according to physician's specialization. In addition, this work aimed to identify key decision factors that practitioners consider in their decision to retreat or not a patient with hyaluronic acid viscosupplementation.

methodsPractitioners have been invited by e-mail to participate in an online exercise on viscosupplementation retreatment. They received a fictional patient case at random among a set of predefined fictional cases. The platform asked the practitioner if he/she would retreat the patient with viscosupplementation or not. To take a decision, the practitioner could select questions among a list of predefined questions. Among them, some were related to criteria used in the EUROVISCO decision tree and others served as confounding factors.

resultsA total of 506 practitioners participated to the exercise, of which 399 gave their decision about the case assigned to them by the platform. The observed agreement between practitioner decisions and EUROVISCO recommendations was 58.89 ± 4.95% (95% confidence interval [CI]). Overall, the decision to retreat was taken in 47.87% of the cases, while the EUROVISCO guidelines follow-up would have led to 55.89% retreatment for the same cases (

conclusionsIn current practice, physicians tended to reinject their patients less than recommended, although EUROVISCO guidelines for viscosupplementation retreatment consider decision criteria that clearly correspond to those of practitioners in real life. These include the patients' willingness to be treated or the patients' perception of the effectiveness of the treatment.

Indexed as

Osteoarthritis, KneeViscosupplementationConsensusFemaleHumansHyaluronic AcidRetreatmentViscosupplementsHyaluronic AcidViscosupplementsguidelineshyaluronic acidkneeosteoarthritisviscosupplementation

Identifiers

PMID34696623
PMCPMC8808890
OpenAlexW3208959394

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.