Evidence map›Paper›PMID 34696526›Full record

ArticleViruses2021

A Perspective on Nanotechnology and COVID-19 Vaccine Research and Production in South Africa.

Admire Dube, Samuel Egieyeh, Mohammed Balogun

Abstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Admire DubeSchool of Pharmacy, University of the Western Cape, Bellville 7535, South Africa.ORCID 0000-0002-5684-6094
Samuel EgieyehSchool of Pharmacy, University of the Western Cape, Bellville 7535, South Africa.ORCID 0000-0002-7462-6669
Mohammed BalogunBiopolymer Modification and Therapeutics Laboratory, Chemicals Cluster, Council for Scientific and Industrial Research, Brummeria, Pretoria 0001, South Africa.

Funding

Development of Nanomedicines for Tuberculosis TreatmentK43TW010371 · FIC · UNIVERSITY OF THE WESTERN CAPE · PI DUBE, ADMIRE · 2017 to 2021
$370k
FIC NIH HHS K43 TW010371FIC NIH HHS K43TW010371Wellcome Trust 109059
6 · The paper itself

Abstract

Advances in nanotechnology have enabled the development of a new generation of vaccines, which are playing a critical role in the global control of the COVID-19 pandemic and the return to normalcy. Vaccine development has been conducted, by and large, by countries in the global north. South Africa, as a major emerging economy, has made extensive investments in nanotechnology and bioinformatics and has the expertise and resources in vaccine development and manufacturing. This has been built at a national level through decades of investment. In this perspective article, we provide a synopsis of the investments made in nanotechnology and highlight how these could support innovation, research, and development for vaccines for this disease. We also discuss the application of bioinformatics tools to support rapid and cost-effective vaccine development and make recommendations for future research and development in this area to support future health challenges.

Indexed as

COVID-19COVID-19 VaccinesNanotechnologyComputational BiologyDrug DevelopmentHumansPandemicsSouth AfricaCOVID-19 Vaccinesbioinformatics and vaccine developmentCOVID-19 and nanotechnologynanomedicine in South Africavaccine development in South Africa

Identifiers

PMID34696526
PMCPMC8539279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.