Evidence map›Paper›PMID 34696418›Full record

ArticleViruses2021

A Multidisciplinary Investigation of the First Chikungunya Virus Outbreak in Matadi in the Democratic Republic of the Congo.

Anja De Weggheleire, Antoine Nkuba-Ndaye, Placide Mbala-Kingebeni, Joachim Mariën, Esaie Kindombe-Luzolo, Gillon Ilombe, Donatien Mangala-Sonzi, Guillaume Binene-Mbuka, Birgit De Smet, Florian Vogt and 11 more

Abstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Behavior of AdultTropical medicine and infectious disease · 2023
    Article
  12. Pattern ofTropical medicine and infectious disease · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Anja De WeggheleireOutbreak Research Team, Institute of Tropical Medicine, 2000 Antwerp, Belgium.ORCID 0000-0001-9377-4766
Antoine Nkuba-NdayeDepartment of Virology, National Institute of Biomedical Research, B.P. 1197 Kinshasa I, Democratic Republic of the Congo.ORCID 0000-0003-2850-7498
Placide Mbala-KingebeniDepartment of Virology, National Institute of Biomedical Research, B.P. 1197 Kinshasa I, Democratic Republic of the Congo.
Joachim MariënOutbreak Research Team, Institute of Tropical Medicine, 2000 Antwerp, Belgium.
Esaie Kindombe-LuzoloDepartment of Virology, National Institute of Biomedical Research, B.P. 1197 Kinshasa I, Democratic Republic of the Congo.
Gillon IlombeDepartment of Entomology, National Institute of Biomedical Research, B.P. 1197 Kinshasa I, Democratic Republic of the Congo.
Donatien Mangala-SonziDepartment of Medical Biology, University of Kinshasa, B.P. 127 Kinshasa IX, Democratic Republic of the Congo.
Guillaume Binene-MbukaDepartment of Entomology, National Institute of Biomedical Research, B.P. 1197 Kinshasa I, Democratic Republic of the Congo.
Birgit De SmetOutbreak Research Team, Institute of Tropical Medicine, 2000 Antwerp, Belgium.ORCID 0000-0002-1790-1900
Florian VogtOutbreak Research Team, Institute of Tropical Medicine, 2000 Antwerp, Belgium.
Philippe SelhorstOutbreak Research Team, Institute of Tropical Medicine, 2000 Antwerp, Belgium.
Mathy Matungala-PafubelDepartment of Medical Biology, University of Kinshasa, B.P. 127 Kinshasa IX, Democratic Republic of the Congo.
Frida NkawaDepartment of Virology, National Institute of Biomedical Research, B.P. 1197 Kinshasa I, Democratic Republic of the Congo.
Fabien VuluDepartment of Medical Biology, University of Kinshasa, B.P. 127 Kinshasa IX, Democratic Republic of the Congo.ORCID 0000-0003-4295-223X
Mathias MossokoDirection de Lutte contre la Maladie, Ministry of Health, B.P. 3040 Kinshasa I, Democratic Republic of the Congo.
Elisabeth Pukuta-SimbuDepartment of Virology, National Institute of Biomedical Research, B.P. 1197 Kinshasa I, Democratic Republic of the Congo.
Eddy Kinganda-LusamakiDepartment of Virology, National Institute of Biomedical Research, B.P. 1197 Kinshasa I, Democratic Republic of the Congo.ORCID 0000-0001-9795-0165
Wim Van BortelOutbreak Research Team, Institute of Tropical Medicine, 2000 Antwerp, Belgium.ORCID 0000-0002-6644-518X
Francis Wat'senga-TezzoDepartment of Entomology, National Institute of Biomedical Research, B.P. 1197 Kinshasa I, Democratic Republic of the Congo.
Sheila Makiala-MandandaDepartment of Virology, National Institute of Biomedical Research, B.P. 1197 Kinshasa I, Democratic Republic of the Congo.
Steve Ahuka-MundekeDepartment of Virology, National Institute of Biomedical Research, B.P. 1197 Kinshasa I, Democratic Republic of the Congo.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early March 2019, health authorities of Matadi in the Democratic Republic of the Congo alerted a sudden increase in acute fever/arthralgia cases, prompting an outbreak investigation. We collected surveillance data, clinical data, and laboratory specimens from clinical suspects (for CHIKV-PCR/ELISA, malaria RDT), semi-structured interviews with patients/caregivers about perceptions and health seeking behavior, and mosquito sampling (adult/larvae) for CHIKV-PCR and estimation of infestation levels. The investigations confirmed a large CHIKV outbreak that lasted February-June 2019. The total caseload remained unknown due to a lack of systematic surveillance, but one of the two health zones of Matadi notified 2686 suspects. Of the clinical suspects we investigated (

Indexed as

AdolescentAdultAedesAgedAnimalsArthralgiaChikungunya FeverChikungunya virusChildChild, PreschoolDemocratic Republic of the CongoDisease OutbreaksFemaleFeverHumansLarvaAedes albopictuschikungunyaDemocratic Republic of the Congomultidisciplinaryoutbreak investigation

Identifiers

PMID34696418
PMCPMC8541179

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.