Evidence map›Paper›PMID 34696370›Full record

ArticleViruses2021

Outbreak of a Systemic Form of Camelpox in a Dromedary Herd (

Sunitha Joseph, Joerg Kinne, Péter Nagy, Jutka Juhász, Rajib Barua, Nissy Annie Georgy Patteril, Donata Hoffmann, Florian Pfaff, Bernd Hoffmann, Ulrich Wernery

Abstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Comparative Pathology of Zoonotic Orthopoxviruses.Pathogens (Basel, Switzerland) · 2022
    Review
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sunitha JosephCentral Veterinary Research Laboratory, Dubai 597, United Arab Emirates.
Joerg KinneCentral Veterinary Research Laboratory, Dubai 597, United Arab Emirates.
Péter NagyFarm and Veterinary Department, Emirates Industry for Camel Milk and Products, Dubai 294236, United Arab Emirates.ORCID 0000-0001-7068-9489
Jutka JuhászFarm and Veterinary Department, Emirates Industry for Camel Milk and Products, Dubai 294236, United Arab Emirates.
Rajib BaruaFarm and Veterinary Department, Emirates Industry for Camel Milk and Products, Dubai 294236, United Arab Emirates.ORCID 0000-0002-7114-666X
Nissy Annie Georgy PatterilCentral Veterinary Research Laboratory, Dubai 597, United Arab Emirates.
Donata HoffmannFriedrich-Loeffler-Institut, Institute of Diagnostic Virology, Suedufer 10, 17493 Greifswald-Insel Riems, Germany.ORCID 0000-0003-4552-031X
Florian PfaffFriedrich-Loeffler-Institut, Institute of Diagnostic Virology, Suedufer 10, 17493 Greifswald-Insel Riems, Germany.ORCID 0000-0003-0178-6183
Bernd HoffmannFriedrich-Loeffler-Institut, Institute of Diagnostic Virology, Suedufer 10, 17493 Greifswald-Insel Riems, Germany.ORCID 0000-0001-5358-6445
Ulrich WerneryCentral Veterinary Research Laboratory, Dubai 597, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Camelpox virus (CMLV) is the causative agent of camelpox, which frequently occurs in the Old World camelids-rearing countries except for Australia. It has also been described in experimentally inoculated New World camelids. Camelpox outbreaks are often experienced shortly after the rainy season, which occurs twice a year on the Arabian Peninsula because of the increased density of the insect population, particularly mosquitos. A systemic form of camelpox outbreak in seven dromedary camels was diagnosed by histology, virus isolation, and PCR. A phylogenetic analysis using full length CMLV genomes of the isolated CMLV strains showed a single phylogenetic unit without any distinctive differences between them. The United Arab Emirates (UAE) isolate sequences showed phylogenetical relatedness with CMLV isolates from Israel with only minor sequence differences. Although the sequences of viruses from both countries were closely related, the disease manifestation was vastly different. Our study shows that the virulence is not only determined by genetic features of CMLV alone but may also depend on other factors such as unknown aspects of the host (e.g., age, overall fitness), management, and the environment.

Indexed as

AnimalsCamelusDisease OutbreaksFemaleHigh-Throughput Nucleotide SequencingMaleOrthopoxvirusPhylogenyPoxviridae InfectionsSequence Analysis, DNAUnited Arab Emiratescamelpoxdromedary camelnext generation sequencingphylogenetic analysissystemic formvirus

Identifiers

PMID34696370
PMCPMC8541543

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.