Evidence map›Paper›PMID 34696299›Full record

ArticleVaccines2021

Seroepidemiology of Measles, Mumps, Rubella and Varicella in Italian Female School Workers: A Cross-Sectional Study.

Nicola Frau, Federico Meloni, Jacopo Fostinelli, Laura Portas, Igor Portoghese, Emma Sala, Ilaria Pilia, Luigi Isaia Lecca, Giuseppe De Palma, Marcello Campagna

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Nicola FrauDepartment of Medical Sciences and Public Health, University of Cagliari, Cittadella Universitaria di Monserrato, SS 554 bivio per Sestu, Monserrato, 09042 Cagliari, Italy.ORCID 0000-0001-6648-4878
Federico MeloniDepartment of Medical Sciences and Public Health, University of Cagliari, Cittadella Universitaria di Monserrato, SS 554 bivio per Sestu, Monserrato, 09042 Cagliari, Italy.ORCID 0000-0001-8120-2103
Jacopo FostinelliDepartment of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, 25123 Brescia, Italy.
Laura PortasNational Heart and Lung Institute, Imperial College London, London SW7 2AZ, UK.ORCID 0000-0003-1789-1893
Igor PortogheseDepartment of Medical Sciences and Public Health, University of Cagliari, Cittadella Universitaria di Monserrato, SS 554 bivio per Sestu, Monserrato, 09042 Cagliari, Italy.ORCID 0000-0003-3700-8594
Emma SalaDepartment of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, 25123 Brescia, Italy.
Ilaria PiliaDepartment of Medical Sciences and Public Health, University of Cagliari, Cittadella Universitaria di Monserrato, SS 554 bivio per Sestu, Monserrato, 09042 Cagliari, Italy.
Luigi Isaia LeccaDepartment of Medical Sciences and Public Health, University of Cagliari, Cittadella Universitaria di Monserrato, SS 554 bivio per Sestu, Monserrato, 09042 Cagliari, Italy.ORCID 0000-0001-8310-411X
Giuseppe De PalmaDepartment of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, 25123 Brescia, Italy.ORCID 0000-0001-9821-3060
Marcello CampagnaDepartment of Medical Sciences and Public Health, University of Cagliari, Cittadella Universitaria di Monserrato, SS 554 bivio per Sestu, Monserrato, 09042 Cagliari, Italy.
University of Cagliari · ITUniversity of Brescia · ITImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDetermining the proportion of susceptible workers can represent a first step to the biological risk assessment related to measles, mumps, rubella and varicella exposure. This study aimed to assess the immunity against measles, mumps, rubella and varicella viruses in a cohort of female school workers.

methodsA cross-sectional seroepidemiological study in a sample of 263 school workers undergoing routine annual workplace health surveillance program was conducted. As part of the health surveillance program, serum samples were collected and tested for measles, mumps, rubella and varicella IgG antibodies.

resultsOverall seropositivity was 90.5%, 85.2%, 94.7% and 97.3% for measles, mumps, rubella and varicella, respectively. In relation to mumps occupation-specific seropositivity, a statistically significant difference was observed, showing the lowest prevalence of protected individuals in other occupation groups. Moreover, in relation to rubella, school workers born in Centre Italy had the lowest seropositivity of protective antibodies and the difference between groups was statistically significant. Measles and rubella seropositivity showed a significant decrease after 2015.

conclusionsThis study showed a relevant proportion of school workers susceptible to the aforementioned diseases. These results highlighted the need for proper health surveillance and immunological controls in school workers, especially for females, and provided useful insights to policymakers to select effective strategies aimed at containing the risk of vaccine-preventable diseases at schools.

Indexed as

early childhood teacherprotective immunitypublic health surveillanceschool teacherseroprevalencevaccine-preventable disease

Identifiers

PMID34696299
PMCPMC8538669
OpenAlexW3207793673

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.