Evidence map›Paper›PMID 34696290›Full record

ArticleVaccines2021

Immune Response in Mice Immunized with Chimeric H1 Antigens.

Erasmus Nikoi Kotey, William Kwabena Ampofo, Rebecca Daines, Jean-Remy Sadeyen, Munir Iqbal, Osbourne Quaye

Abstract read
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Erasmus Nikoi KoteyWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Legon, Accra 23321, Ghana.
William Kwabena AmpofoNoguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra 23321, Ghana.
Rebecca DainesThe Pirbright Institute, Ash Road, Pirbright, Woking GU24 0NF, UK.
Jean-Remy SadeyenThe Pirbright Institute, Ash Road, Pirbright, Woking GU24 0NF, UK.
Munir IqbalThe Pirbright Institute, Ash Road, Pirbright, Woking GU24 0NF, UK.ORCID 0000-0001-5165-5339
Osbourne QuayeWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Legon, Accra 23321, Ghana.ORCID 0000-0002-0621-876X

Funding

Biotechnology and Biological Sciences Research Council BBS/E/I/00007031World Bank Group ACE02-WACCBIP: Awandare
6 · The paper itself

Abstract

Identification of a universal influenza vaccine candidate has remained a global challenge for both humans and animals. This study describes an approach that uses consensus sequence building to generate chimeric HAs (cHAs): two resultant H1 HA-based chimeras comprising of conserved sequences (within several areas spanning the head and stalk regions) of H1 and H5 or H9 HAs. These cHAs expressed in

Indexed as

broad-reactive antibodieschimeric haemagglutinincross-reactivityprophylacticseasonal influenzatherapeuticuniversal influenza vaccine

Identifiers

PMID34696290
PMCPMC8538909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.