ArticleVaccines2021
Vaccinating Adolescents and Children Significantly Reduces COVID-19 Morbidity and Mortality across All Ages: A Population-Based Modeling Study Using the UK as an Example.
Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Review
- The cost-effectiveness of COVID-19 vaccination program among age-groups children, adults, and elderly in Europe: A systematic review.Vaccine: X · 2024Review
- Myocarditis Associated with COVID-19 Vaccination.Vaccines · 2024Review
- The effectiveness of the COVID-19 vaccines in the prevention of post-COVID conditions in children and adolescents: a systematic literature review and meta-analysis.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2024Article
- A population-based paediatric Covid-19 vaccination progress and outcomes: The Malta case.Ethics, medicine, and public health · 2023Article
- High anti-SARS-CoV-2 seroprevalence among unvaccinated mother-child pairs from a rural setting in north-eastern Tanzania during the second wave of COVID-19.IJID regions · 2023Article
- Pediatricians' experiences of managing outpatient care during the COVID-19 pandemic: A qualitative study in Germany.Frontiers in pediatrics · 2023Article
- Article
- Modeling COVID-19 Transmission Dynamics: A Bibliometric Review.International journal of environmental research and public health · 2022Review
- Neuropsychiatric Disorders in Pediatric Long COVID-19: A Case Series.Brain sciences · 2022Article
- Adolescent COVID-19 Vaccine Decision-Making among Parents in Southern California.International journal of environmental research and public health · 2022Article
- The Population-Wide Risk-Benefit Profile of Extending the Primary COVID-19 Vaccine Course Compared with an mRNA Booster Dose Program.Vaccines · 2022Article
- Reasons in favour of universal vaccination campaign against COVID-19 in the pediatric population.Italian journal of pediatrics · 2022Article
- Unvaccinated Children Are an Important Link in the Transmission of SARS-CoV-2 Delta Variant (B1.617.2): Comparative Clinical Evidence From a Recent Community Surge.Frontiers in cellular and infection microbiology · 2022Article
- COVID-19 Pediatric Vaccine Hesitancy among Racially Diverse Parents in the United States.Vaccines · 2021Article
- The COVID-19 pandemic in children and young people during 2020-2021: A complex discussion on vaccination.Journal of global healthArticle
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
Debate persists around the risk-benefit balance of vaccinating adolescents and children against COVID-19. Central to this debate is quantifying the contribution of adolescents and children to the transmission of SARS-CoV-2, and the potential impact of vaccinating these age groups. In this study, we present a novel SEIR mathematical disease transmission model that quantifies the impact of different vaccination strategies on population-level SARS-CoV-2 infections and clinical outcomes. The model employs both age- and time-dependent social mixing patterns to capture the impact of changes in restrictions. The model was used to assess the impact of vaccinating adolescents and children on the natural history of the COVID-19 pandemic across all age groups, using the UK as an example. The base case model demonstrates significant increases in COVID-19 disease burden in the UK following a relaxation of restrictions, if vaccines are limited to those ≥18 years and vulnerable adolescents (≥12 years). Including adolescents and children in the vaccination program could reduce overall COVID-related mortality by 57%, and reduce cases of long COVID by 75%. This study demonstrates that vaccinating adolescents and children has the potential to play a vital role in reducing SARS-CoV-2 infections, and subsequent COVID-19 morbidity and mortality, across all ages. Our results have major global public health implications and provide valuable information to inform a potential pandemic exit strategy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.