Evidence map›Paper›PMID 34696199›Full record

ArticleVaccines2021

The Potential Adjuvanticity of CAvant

Young-Hoon Ahn, W A Gayan Chathuranga, Young-Jung Shim, D K Haluwana, Eun-Hee Kim, In-Joong Yoon, Yong-Taik Lim, Sung Ho Shin, Hyundong Jo, Seong Yun Hwang and 5 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Young-Hoon AhnChoong Ang Vaccine Laboratory Co., Ltd., Daejeon 34055, Korea.
W A Gayan ChathurangaCollege of Veterinary Medicine, Chungnam National University, Daejeon 34314, Korea.ORCID 0000-0001-8348-727X
Young-Jung ShimChoong Ang Vaccine Laboratory Co., Ltd., Daejeon 34055, Korea.
D K HaluwanaCollege of Veterinary Medicine, Chungnam National University, Daejeon 34314, Korea.
Eun-Hee KimChoong Ang Vaccine Laboratory Co., Ltd., Daejeon 34055, Korea.
In-Joong YoonChoong Ang Vaccine Laboratory Co., Ltd., Daejeon 34055, Korea.
Yong-Taik LimDepartment of Nano Engineering, Sungkyunkwan University, Suwon 16419, Korea.
Sung Ho ShinAnimal and Plant Quarantine Agency, Gimcheon 39660, Korea.
Hyundong JoAnimal and Plant Quarantine Agency, Gimcheon 39660, Korea.
Seong Yun HwangAnimal and Plant Quarantine Agency, Gimcheon 39660, Korea.
Hyun Mi KimAnimal and Plant Quarantine Agency, Gimcheon 39660, Korea.
Min Ja LeeAnimal and Plant Quarantine Agency, Gimcheon 39660, Korea.ORCID 0000-0002-5916-5083
Jong-Hyeon ParkAnimal and Plant Quarantine Agency, Gimcheon 39660, Korea.ORCID 0000-0003-0825-8121
Sung-Sik YooChoong Ang Vaccine Laboratory Co., Ltd., Daejeon 34055, Korea.
Jong-Soo LeeCollege of Veterinary Medicine, Chungnam National University, Daejeon 34314, Korea.ORCID 0000-0001-5119-0711
Animal and Plant Quarantine Agency · KRChungnam National University · KRSungkyunkwan University · KR

Funding

National Research Foundation of Korea 2018M3A9H4078692National Research Foundation of Korea 2018M3A9H4078703National Research Foundation of Korea 2021R1A6A1A03045495
6 · The paper itself

Abstract

Foot-and-mouth disease (FMD) is a notifiable contagious disease of cloven-hoofed mammals. A high potency vaccine that stimulates the host immune response is the foremost strategy used to prevent disease persistence in endemic regions. FMD vaccines comprise inactivated virus antigens whose immunogenicity is potentiated by immunogenic adjuvants. Oil-based adjuvants have clear advantages over traditional adjuvant vaccines; however, there is potential to develop novel adjuvants to increase the potency of FMD vaccines. Thus, we aimed to evaluate the efficacy of a novel water-in-oil emulsion, called CAvant

Indexed as

adjuvantCAvant®SOEfoot-and-mouth disease virusvaccinewater-in-oil emulsion

Identifiers

PMID34696199
PMCPMC8539697
OpenAlexW3203714234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.