Evidence map›Paper›PMID 34696155›Full record

SynthesisSensors (Basel, Switzerland)2021

Effect of Blue Light on Acne Vulgaris: A Systematic Review.

Mara Lúcia Gonçalves Diogo, Thalita Molinos Campos, Elsa Susana Reis Fonseca, Christiane Pavani, Anna Carolina Ratto Tempestini Horliana, Kristianne Porta Santos Fernandes, Sandra Kalil Bussadori, Francisca Goreth Malheiro Moraes Fantin, Diego Portes Vieira Leite, Ângela Toshie Araki Yamamoto and 2 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
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  6. Self-care methods use for acne treatment among health science students.Exploratory research in clinical and social pharmacy · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Mara Lúcia Gonçalves DiogoBiophotonics Applied to Health Sciences Department, Nove de Julho University (UNINOVE), Vergueiro 245, São Paulo 01504-001, Brazil.
Thalita Molinos CamposBiophotonics Applied to Health Sciences Department, Nove de Julho University (UNINOVE), Vergueiro 245, São Paulo 01504-001, Brazil.
Elsa Susana Reis FonsecaPhysics Department Covilhã, Universidade da Beira Interior, 6200-354 Covilhã, Portugal.
Christiane PavaniBiophotonics Applied to Health Sciences Department, Nove de Julho University (UNINOVE), Vergueiro 245, São Paulo 01504-001, Brazil.
Anna Carolina Ratto Tempestini HorlianaBiophotonics Applied to Health Sciences Department, Nove de Julho University (UNINOVE), Vergueiro 245, São Paulo 01504-001, Brazil.
Kristianne Porta Santos FernandesBiophotonics Applied to Health Sciences Department, Nove de Julho University (UNINOVE), Vergueiro 245, São Paulo 01504-001, Brazil.ORCID 0000-0001-7156-9286
Sandra Kalil BussadoriBiophotonics Applied to Health Sciences Department, Nove de Julho University (UNINOVE), Vergueiro 245, São Paulo 01504-001, Brazil.
Francisca Goreth Malheiro Moraes FantinDepartment of Bioengineering, Universidade Brasil, São Paulo 08230-030, Brazil.
Diego Portes Vieira LeiteDepartment of Bioengineering, Universidade Brasil, São Paulo 08230-030, Brazil.
Ângela Toshie Araki YamamotoDentistry Department, Universidade Cruzeiro do Sul, São Paulo 01311-925, Brazil.
Ricardo Scarparo NavarroDepartment of Bioengineering, Universidade Brasil, São Paulo 08230-030, Brazil.
Lara Jansiski MottaBiophotonics Applied to Health Sciences Department, Nove de Julho University (UNINOVE), Vergueiro 245, São Paulo 01504-001, Brazil.
Universidade Nove de Julho · BRUniversidade Brasil · BRUniversidade Cruzeiro do Sul · BRUniversity of Beira Interior · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acne is a dermatosis that affects almost 90% of the adolescent population worldwide and its treatment is performed with retinoids, antimicrobials, acids, and topical or systemic antibiotics. Side effects such as skin irritation in addition to microbial resistance to antibiotics are the main side effects found. Phototherapy with blue light is being used as an alternative treatment. Our objective was to analyze the use of blue light to treat inflammatory acne. We conducted a systematic literature review, following the recommendation PRISMA (Preferred Reporting Items for Systematic Reviews and MetaAnalyses), including in the sample randomized clinical trial studies that compared blue light with another intervention as control. The research was carried out in the PUBMED and WEB of SCIENCE databases and the methodological quality of the studies evaluated were made by the Cochrane Collaboration Bias Risk Scale. After the exclusion of duplicates, the titles and abstracts of 81 articles were evaluated, and 50 articles were selected for full reading, including in the review at the end 8 articles. Studies have shown significant improvements in the overall picture of acne. It is concluded that despite the great potential in its use in the treatment of acne, there is a need for more detailed trials on the effect of blue light on the treatment of inflammatory acne.

Indexed as

Acne VulgarisAdolescentAnti-Bacterial AgentsData ManagementHumansLightPhototherapyRandomized Controlled Trials as TopicTreatment OutcomeAnti-Bacterial Agentsacneblue lightLED (Light Emitting Diode)LLLT (Low Level Light Therapy)photobiomodulationphototherapy

Identifiers

PMID34696155
PMCPMC8537635
OpenAlexW3207331377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.