ArticleJournal of affective disorders2022
Screening for depression with the PHQ-9 in young adults affected by HIV.
Article in Journal of affective disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 18 citations in OpenAlex.
- Depression and loneliness among Sub-Saharan immigrants living in the greater Paris area: results from the MAKASI empowerment stepped wedge cluster randomised controlled trial.Social psychiatry and psychiatric epidemiology · 2024Trial
- Variability in daily stressors and depressed mood in the context of chronic HIV stressors.Journal of affective disorders · 2026Article
- Substance use and mental health factors associated with self-reported higher risk cannabis use among people with HIV screened in primary care.BMC public health · 2025Article
- Risk Factors for Viral Non-suppression Among Youth Living with HIV in Nigeria: Findings from the iCARE Nigeria Study.AIDS and behavior · 2025Article
- Network of job demands-resources and depressive symptoms in critical care nurses: a nationwide cross-sectional study.Critical care (London, England) · 2025Article
- Impact of postoperative depression and immune-inflammatory biomarkers on the prognosis of patients with esophageal cancer receiving minimally invasive esophagectomy: a retrospective cohort study based on a Chinese population.Frontiers in immunology · 2025Article
- Sociodemographic and behavioral characteristics of older people with HIV in Almaty City, Kazakhstan: A cross-sectional study.PloS one · 2025Article
- Understanding depression and the PHQ-9 items among people living with HIV: A multiple methods qualitative study in Yaoundé, Cameroon.SSM. Mental health · 2024Article
- Optimizing generalized anxiety disorder screening in young adults perinatally affected by HIV: A psychometric analysis.Journal of mood and anxiety disorders · 2024Article
- Association of Gastrointestinal Symptoms with Depression and Anxiety in Recruits: A Validation Cross-Sectional Study.Advances in therapy · 2024Article
- Pilot study assessing gut microbial diversity among sexual and gender minority young adults.PloS one · 2024Article
- Mental health burden among females living with HIV and AIDS in sub-Saharan Africa: A systematic review.PLOS global public health · 2024Article
- Long-Term Post-Transition Outcomes of Adolescents and Young Adults Living With Perinatally and Non-perinatally Acquired HIV in Southeast Asia.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2023Article
- Profiles of depressive symptoms and influential factors among people living with HIV in China.BMC public health · 2023Article
- Suicidal Ideation and Attempts Among Youth Living With HIV/AIDS Attending Botswana-Baylor Children's Clinical Centre of Excellence: A Comparison Between Substance Users and Non-Substance Users.Substance use : research and treatmentArticle
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7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundMajor depressive disorder (MDD) is common among young adults with perinatally acquired HIV (YAPHIV), however it is often underdiagnosed and untreated. The PHQ-9 and PHQ-2 are widely used screening instruments for MDD. This study evaluates the accuracy of recommended PHQ-9 and PHQ-2 cut-scores of 10 and 3 for YAPHIV and YA who were perinatally HIV exposed but uninfected (YAPHEU).
methodsThe PHQ-9 was administered to participants (n = 203) in a longitudinal cohort study using the DISC-IV as the gold standard for diagnosing depression. PHQ-9 and PHQ-2 sensitivity and specificity were calculated. ROC curves were constructed for the overall sample and YAPHIV and YAPHEU subsamples.
resultsAlmost all participants were Black and Latinx, ages 18-29. Overall, the recommended PHQ-9 cut-score of ≥10 yielded a sensitivity of 0.47 (95%CI [0.23,0.72]) and specificity of 0.86 (95%CI [0.80, 0.91]). Results indicate that PHQ-9 cut-scores of 7 and PHQ-2 cut-scores of 2 increased sensitivity to 0.76 (95%CI [0.50, 0.93]) and 0.71(95%CI [0.44,0.90]), and decreased specificity to 0.72 (95%CI [0.65, 0.79]) and 0.73 (95%CI [0.66, 0.79]) respectively. Among subsamples, existing PHQ-9 cut-scores were more accurate for MDD diagnoses in YAPHEU (N = 11) than YAPHIV(N = 6). No race/ethnicity or age differences were found. LIMITATIONS: Participants were recruited from clinics in NYC and may not reflect all YAPHIV and YAPHEU. Without a white HIV comparison group, no conclusions could be made on the impact of race/ethnicity on optimized PHQ-9 cut-scores.
conclusionsUsing tailored cut scores for HIV-affected populations may increase identification of those experiencing or at risk for MDD. Given the need for increased depression screening in HIV care, use of optimized cut-scores could benefit at-risk populations in the US and globally.
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