ArticleIET nanobiotechnology2021
Observation of targeted gold nanoparticles in nasopharyngeal tumour nude mice model through dual-energy computed tomography.
Article in IET nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
- Observation of targeted gold nanoparticles in nasopharyngeal tumour nude mice model through dual-energy computed tomography.IET nanobiotechnology · 2021Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
This study was performed to specify the efficiency of imaging nanoparticle concentration as contrast media in dual-energy computed tomography (DECT). Gold nanoparticles (AuNPs) and gold nanoparticles-conjugated folic acid through cysteamine (FA-Cya-AuNPs) were both considered as contrast agents. Characterization of NPs was performed using Dynamic Light Scattering (DLS) and zeta potential. The hemocompatibility of NPs was confirmed by different blood parameters such as white blood cell, red cell distribution width, hemoglobin, lymphocytes counts and haemolysis assay. DECT algorithm was confirmed using calibration phantom at different concentrations of NPs and tube potentials (80 and 140 kVp). Then, DECT was used to quantify the concentration of both AuNPs and FA-Cys-AuNPs in human nasopharyngeal cancer cells. Mice were injected with non-targeted AuNPs and targeted AuNps at a concentration of 3 × 10
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Registered trials
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