Observational studyJournal of clinical oncology : official journal of the American Society of Clinical Oncology2021
SARS-CoV-2 in Childhood Cancer in 2020: A Disease of Disparities.
Observational study in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- COVID-19 infection in children with blood cancer: A systematic review.Annals of hematology · 2025Pooled it
- The Global Impact of COVID-19 on Childhood Cancer Outcomes and Care Delivery - A Systematic Review.Frontiers in oncology · 2022Pooled it
- Is COVID-19 Still a Threat? An Expert Opinion Review on the Continued Healthcare Burden in Immunocompromised Individuals.Advances in therapy · 2025Review
- Increased Early-Mortality in Children With Solid Tumors During the COVID-19 Pandemic in a Middle-Income Country.Cancer medicine · 2024Article
- Immunophenotype of lymphocytes and real-world outcome of COVID-19 infection in children with hematology and oncology.BMC cancer · 2024Article
- COVID-19 in Pediatric Patients With Acute Lymphoblastic Leukemia or Lymphoma.JAMA network open · 2024Article
- Article
- Humoral profiling of pediatric patients with cancer reveals robust immunity following anti-SARS-CoV-2 vaccination superior to natural infection.Pediatric blood & cancer · 2023Article
- Risk of COVID-19 infection in long-term survivors of blood or marrow transplantation: a BMTSS report.Blood advances · 2023Article
- Psychosocial impact of COVID-19 on caregivers and adolescents and young adult survivors of childhood cancer.Pediatric blood & cancer · 2023Article
- SARS-CoV-2 infections in pediatric and young adult recipients of chimeric antigen receptor T-cell therapy: an international registry report.Journal for immunotherapy of cancer · 2023Article
- COVID-19 outcomes in children, adolescents and young adults with cancer.International journal of cancer · 2022Article
- Low numbers of COVID-19 in Swedish pediatric oncology patients during the first pandemic year despite an open society.Pediatric blood & cancer · 2022Article
- COVID-19-Associated Pulmonary Fungal Infection among Pediatric Cancer Patients, a Single Center Experience.Journal of fungi (Basel, Switzerland) · 2022Article
- Neutropenia and Infection Prophylaxis in Childhood Cancer.Current oncology reports · 2022Review
- How the COVID-19 Pandemic Reshaped the Management of Leukemia and Affected Patient Outcomes.Current treatment options in oncology · 2022Review
- Factors that predict severity of infection and seroconversion in immunocompromised children and adolescents with COVID-19 infection.Frontiers in immunology · 2022Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe Pediatric Oncology COVID-19 Case Report registry supplies pediatric oncologists with data surrounding the clinical course and outcomes in children with cancer and SARS-CoV-2.
methodsThis observational study captured clinical and sociodemographic characteristics for children (≤ 21 years) receiving cancer therapy and infected with SARS-CoV-2 from the pandemic onset through February 19, 2021. The demographic and clinical characteristics of the cohort were compared with population-level pediatric oncology data (SEER). Multivariable binomial regression models evaluated patient characteristics associated with hospitalization, intensive care unit (ICU) admission, and changes in cancer therapy.
resultsNinety-four institutions contributed details on 917 children with cancer and SARS-CoV-2. Median age at SARS-CoV-2 infection was 11 years (range, 0-21 years). Compared with SEER, there was an over-representation of Hispanics (43.6%
conclusionThese findings provide critical information for decision making among pediatric oncologists, including inpatient versus outpatient management, cancer therapy modifications, consideration of monoclonal antibody therapy, and counseling families on infection risks in the setting of the SARS-CoV-2 pandemic. The over-representation of Hispanic and publicly insured patients in this national cohort suggests disparities that require attention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.