Evidence map›Paper›PMID 34694721›Full record

ArticleIET nanobiotechnology2021

Design of 3-aminophenol-grafted polymer-modified zinc sulphide nanoparticles as drug delivery system.

Milad Abniki, Zahra Azizi, Homayon Ahmad Panahi

Open access · goldAbstract read
In one paragraph

Article in IET nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Milad AbnikiDepartment of Chemistry, Karaj Branch, Islamic Azad University, Karaj, Iran.
Zahra AziziDepartment of Chemistry, Karaj Branch, Islamic Azad University, Karaj, Iran.ORCID https://orcid.org/0000-0001-5255-8311
Homayon Ahmad PanahiDepartment of Chemistry, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Islamic Azad University, Karaj · IRIslamic Azad University Central Tehran Branch · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zinc sulphide (ZnS) nanoparticles were synthesized by the coprecipitation method. The ZnS nanoparticle surface was polymerized with allyl glycidyl ether (AGE), and 3-aminophenol was then deposited as a ligand on nanosorbent. The modified nanosorbent was investigated with Fourier transform infrared spectroscopy and thermogravimetric analysis. The particle size of the modified nanosorbent was studied with scanning electron microscopy. Some characteristic factors of the adsorption process such as pH and time were investigated for famotidine using the modified nanosorbent. The equilibrium adsorption study of famotidine by 3-aminophenol-grafted AGE/ZnS was analysed by adsorption isotherms of the Langmuir, Freundlich, and Temkin models. The famotidine-releasing process was investigated in simulated biological fluids (intestinal fluid at pH of 7.4 and gastric fluid at pH of 1.2) and demonstrated 65% and 73% famotidine release during periods of 30 h (pH = 7.4) and 60 min (pH = 1.2), respectively. These results reveal the optimal performance of 3-aminophenol-grafted AGE/ZnS for sustained drug delivery.

Indexed as

Magnetite NanoparticlesNanoparticlesAdsorptionAminophenolsDrug Delivery SystemsHydrogen-Ion ConcentrationKineticsPolymersSpectroscopy, Fourier Transform InfraredSulfidesZinc Compounds3-aminophenolAminophenolsMagnetite NanoparticlesPolymersSulfidesZinc Compoundszinc sulfide

Identifiers

PMID34694721
PMCPMC8675825
OpenAlexW3171910507

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.