ArticleArtificial organs2022
Outcomes after extracorporeal membrane oxygenation support in COVID-19 and non-COVID-19 patients.
Article in Artificial organs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Extracorporeal membrane oxygenation initiation timing and prognosis: a systematic review and meta-analysis.BMC cardiovascular disorders · 2026Pooled it
- Anticoagulation optimization and clinical impact of post-transplant deep vein thrombosis: clinical impact and a VV-ECMO subgroup analysis.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2026Article
- Impact of pre-transplant veno-venous extracorporeal membrane oxygenation on post-lung transplant infections.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025Article
- Contrasting predictors of severe primary graft dysfunction following transplant for chronic and acute respiratory failure.Journal of thoracic disease · 2024Article
- Impact of bridging veno-venous extracorporeal membrane oxygenation to COVID-19 lung transplantation.Journal of thoracic disease · 2024Article
- Pulmonary perfusion in long-term survivors of COVID-19-related severe acute respiratory distress syndrome treated by extracorporeal membrane oxygenation.Pulmonary circulation · 2024Article
- Temporal correlation between postreperfusion complement deposition and severe primary graft dysfunction in lung allografts.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024Article
- Risk Factors for the Mortality of Patients With Coronavirus Disease 2019 Requiring Extracorporeal Membrane Oxygenation in a Non-Centralized Setting: A Nationwide Study.Journal of Korean medical science · 2024Article
- Variation in outcomes with extracorporeal membrane oxygenation in the era of coronavirus: A multicenter cohort evaluation.Perfusion · 2023Observational
- The role of ECMO in COVID-19 acute respiratory failure: Defining risk factors for mortality.American journal of surgery · 2023Article
- Early initiation of physical and occupational therapy while on extracorporeal life support improves patients' functional activity.Artificial organs · 2023Article
- Article
- Bleeding and Thrombotic Complications in COVID-19-Associated ARDS Requiring ECMO.Respiratory care · 2023Observational
- Lung Transplantation for Coronavirus Disease-2019 Patients and Coronavirus Disease-2019 in Lung Transplant Recipients.Clinics in chest medicine · 2023Review
- Lessons learned by thoracic surgeons during the COVID-19 pandemic.Journal of thoracic disease · 2023Article
- Extracorporeal membrane oxygenation for COVID-19-related acute respiratory distress syndrome: a narrative review.Journal of intensive care · 2023Review
- Extracorporeal Membrane Oxygenation for COVID-19: Comparison of Outcomes to Non-COVID-19-Related Viral Acute Respiratory Distress Syndrome From the Extracorporeal Life Support Organization Registry.Critical care explorations · 2023Article
- Management of two circulations in a COVID-19 patient with secondary superinfection.Physiological reports · 2023Article
- Outcomes of Extracorporeal Membrane Oxygenation in COVID-19-Induced Acute Respiratory Distress Syndrome: An Inverse Probability Weighted Analysis.Critical care explorations · 2022Article
- Coagulation abnormalities in patients with COVID-19 on venovenous ECLS increased risk for technical complications and support times but had no impact on survival.Artificial organs · 2022Article
Corrections and comments
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Authors and funding
17 authors at 1 institution in 1 country.
Funding
Abstract
backgroundVeno-venous extracorporeal membrane oxygenation (V-V ECMO) support is increasingly used in the management of COVID-19-related acute respiratory distress syndrome (ARDS). However, the clinical decision-making to initiate V-V ECMO for severe COVID-19 still remains unclear. In order to determine the optimal timing and patient selection, we investigated the outcomes of both COVID-19 and non-COVID-19 patients undergoing V-V ECMO support.
methodsOverall, 138 patients were included in this study. Patients were stratified into two cohorts: those with COVID-19 and non-COVID-19 ARDS.
resultsThe survival in patients with COVID-19 was statistically similar to non-COVID-19 patients (p = .16). However, the COVID-19 group demonstrated higher rates of bleeding (p = .03) and thrombotic complications (p < .001). The duration of V-V ECMO support was longer in COVID-19 patients compared to non-COVID-19 patients (29.0 ± 27.5 vs 15.9 ± 19.6 days, p < .01). Most notably, in contrast to the non-COVID-19 group, we found that COVID-19 patients who had been on a ventilator for longer than 7 days prior to ECMO had 100% mortality without a lung transplant.
conclusionsThese findings suggest that COVID-19-associated ARDS was not associated with a higher post-ECMO mortality than non-COVID-19-associated ARDS patients, despite longer duration of extracorporeal support. Early initiation of V-V ECMO is important for improved ECMO outcomes in COVID-19 ARDS patients. Since late initiation of ECMO was associated with extremely high mortality related to lack of pulmonary recovery, it should be used judiciously or as a bridge to lung transplantation.
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