Evidence map›Paper›PMID 34694575›Full record

ReviewHeart failure reviews2022

Epidemiology and clinical manifestations of cardiac amyloidosis.

Farhan Bajwa, Ryan O'Connor, Karthikeyan Ananthasubramaniam

Abstract readReview
PubMed Publisher
In one paragraph

Review in Heart failure reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 42 citations in OpenAlex.

  1. Observational
  2. Cardiac amyloidosis: From diagnosis to therapeutics breakthroughs.World journal of experimental medicine · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. The Arrhythmic Burden of Cardiac Amyloidosis: A Comprehensive Review.Heart views : the official journal of the Gulf Heart Association · 2026
    Review
  7. Review
  8. Total-bodyEuropean journal of nuclear medicine and molecular imaging · 2025
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Single photon emission computed tomography pyrophosphate imaging for transthyretin cardiac amyloid.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Farhan BajwaDepartment of Cardiology, University of Rochester Medical Center, Rochester, NY, USA.
Ryan O'ConnorDepartment of Cardiology, University of Rochester Medical Center, Rochester, NY, USA.
Karthikeyan AnanthasubramaniamHenry Ford West Bloomfield Hospital, Heart and Vascular Institute, West Bloomfield, MI, 48322, USA. kananth1@hfhs.org.ORCID 0000-0001-5837-496X
University of Rochester Medical Center · USHenry Ford Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac amyloidosis, once considered a rare disease, has garnered significant attention over the last few years due to three key reasons: first, increased recognition of this disease in conjunction with various common cardiac conditions such as heart failure with preserved ejection fraction and aortic stenosis; second, due to the advent of promising new therapies for light chain disease (AL), transthyretin (ATTR) cardiomyopathy, and amyloid neuropathy; finally, the advancements in cardiac imaging including echocardiography, magnetic resonance imaging, and nuclear cardiac scintigraphy aid in non-biopsy diagnosis of ATTR cardiac amyloidosis. The hereditary forms of ATTR have further come into importance with the availability of genetic testing and increased prevalence of certain mutations in African Americans. Recognition of non-cardiac clues to this disease has gained importance and reiterates that high clinical suspicion, detailed patient history, and examination with appropriate use of imaging are vital to confirm the diagnosis.

Indexed as

Amyloid Neuropathies, FamilialAmyloidosisAortic Valve StenosisCardiomyopathiesHeart FailureEchocardiographyHumansAmyloidosisAortic stenosisCardiac amyloidosisClinical manifestationsEpidemiologyHeart failureLight chain cardiac amyloidosisTransthyretin cardiac amyloidosis

Identifiers

PMID34694575
OpenAlexW3209969227

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.