Evidence map›Paper›PMID 34694502›Full record

ArticleLasers in medical science2022

The effect of photodynamic therapy by gold nanoparticles on Streptococcus mutans and biofilm formation: an in vitro study.

Fatemeh Lavaee, Mohammad Motamedifar, Ghazal Rafiee

Abstract read
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In one paragraph

Article in Lasers in medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fatemeh LavaeeOral and Dental Disease Research Center, Oral and Maxillofacial Medicine Department, School of Dentistry, Shiraz University of Medical Sciences, Zand Street, Shiraz, Iran.
Mohammad MotamedifarHIV/AIDS Research Center, Institute of health, Shiraz University of Medical Sciences, Shiraz, Iran. motamedm@sums.ac.ir.ORCID http://orcid.org/0000-0003-4993-4034
Ghazal RafieeStudent Research Committee, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.

Funding

Vice-Chancellor for Research, Shiraz University of Medical Sciences 11909
6 · The paper itself

Abstract

In this experimental study, we aimed to evaluate the antibacterial and anti-biofilm effects of photodynamic therapy with a photosensitizer in conjunction with Gold nanoparticles against Streptococcus mutans as an important cariogenic bacterial agent. This experimental in vitro study evaluated the antibacterial and anti-biofilm effect of five groups as followed against S. mutans: methylene blue (MB), Gold nanoparticles (AuNPs), methylene blue conjugated with Gold nanoparticles (MB-AuNPs), MB mediated photodynamic therapy (MB mediated PDT) and methylene blue conjugated with Gold nanoparticles mediated photodynamic therapy (MB-AuNPs mediated PDT). InGaAlP laser (Azor-2 K) with 25 mW total output, 660 nm wavelength and laser probe cross-section of 0.78 cm

Indexed as

Metal NanoparticlesPhotochemotherapyBiofilmsGoldMethylene BluePhotosensitizing AgentsStreptococcus mutansGoldMethylene BluePhotosensitizing AgentsBiofilmCell survivalLow level llaser therapies

Identifiers

PMID34694502

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.