SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022
The prevalence of frailty among breast cancer patients: a systematic review and meta-analysis.
Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.
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Who cites it
36 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Frequency of use and characterization of frailty assessments in observational studies on older women with breast cancer: a systematic review.BMC geriatrics · 2024Pooled it
- Prevalence and Impact of Frailty in Pancreatic Cancer: A Systematic Review and Meta-Analysis Based on 35,191 Patients.Annals of surgical oncology · 2024Pooled it
- Frailty worsens long-term survival in patients with colorectal cancer: a systematic review and meta-analysis.Frontiers in oncology · 2024Pooled it
- Article
- The FINE Index: A Frailty- and Immunonutrition-Based Nomogram for Survival in Geriatric Breast Cancer: A Retrospective Study.Cancer medicine · 2026Article
- EBCC-15 manifesto: Removing age-related barriers to improve equity in breast cancer care.Breast (Edinburgh, Scotland) · 2026Review
- Frailty and associated factors in women aged 65 years and older with breast cancer: a cross-sectional study.BMC geriatrics · 2026Article
- Frailty transitions and associated factors in older cancer survivors in the USA: using a multi-state modeling.Journal of cancer survivorship : research and practice · 2026Article
- Prevalence of preoperative multidimensional frailty and associated factors in middle-aged and older patients with newly diagnosed breast cancer: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Prevalence of Malnutrition, Frailty, and Cachexia Across Different Cancer Subtypes: Distribution by Age (<65 and ≥65).Journal of clinical medicine · 2026Article
- Efficiency of Sorting Site of Care for Frail Patients Undergoing Mastectomy.Annals of surgical oncology · 2026Article
- Prevalence and predictors of frailty among older patients with lung cancer: a systematic review and meta-analysis.Journal of thoracic disease · 2026Article
- Association between frailty and breast cancer incidence and construction of a breast cancer prediction model based on machine learning.Frontiers in public health · 2026Article
- Frailty Meets Cardio-oncology: A New Frontier in Personalised Cancer Care.European cardiology · 2026Review
- Development and validation of a risk prediction model for postoperative frailty in breast cancer patients.PeerJ · 2026Article
- Constructing and evaluating a predictive model for the risk of preoperative frailty in breast cancer patients.BMC women's health · 2025Article
- Emergency department attendance stratified by cause and frailty status: A national retrospective cohort study.Geriatrics & gerontology international · 2025Article
- Observational
- Article
- The development and validation testing of a comprehensive frailty assessment in women with breast cancer.BMC women's health · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCoexistence of frailty and breast cancer (BC) is related to a higher risk of hospitalization, mortality, and falls. Given the potential reversibility of frailty, investigating its epidemiology in BC is of great importance. However, estimates of the prevalence of frailty in BC patients vary considerably. We synthesized the existing body of literature on the prevalence of frailty among BC patients.
methodsWe searched English databases (Cochrane Library, PubMed, Medline, CINAHL, Embase, Scopus, and Web of Science) and Chinese databases (CNKI, WanFang, CBM, and VIP database) from the inception to April 15, 2021, and collected observational studies about the prevalence of frailty among BC patients. The robustness of the pooled estimates was validated by analysis of different subgroups, meta-regression, and sensitivity. All data were analyzed using Stata 15.1.
resultsIn total, 4645 articles were screened and data from 24 studies involving 13,510 subjects were used in the meta-analysis. The prevalence of frailty among BC patients in individual studies varied from 5 to 71%. The pooled prevalence of frailty was 43% (95% confidence intervals (CI): 36% to 50%, I
conclusionsThe prevalence of frailty among BC patients was relatively high, and the conditions of BC treatment can increase the risk of frailty. Understanding the effects of frailty on BC, especially in elderly patients, can provide the healthcare personnel with the theoretical basis for patients' management and treatment.
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