Evidence map›Paper›PMID 34694472›Full record

ArticleEuropean child & adolescent psychiatry2023

Lower help-seeking intentions mediate subsequent depressive symptoms among adolescents with high autistic traits: a population-based cohort study.

Mariko Hosozawa, Syudo Yamasaki, Shuntaro Ando, Kaori Endo, Yuko Morimoto, Sho Kanata, Shinya Fujikawa, Noriko Cable, Hiroyasu Iso, Mariko Hiraiwa-Hasegawa and 2 more

Open access · hybridAbstract read
In one paragraph

Article in European child & adolescent psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 2 countries.

Mariko HosozawaInstitute for Global Health Policy Research, Bureau of International Health Cooperation, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan. mhosozawa@it.ncgm.go.jp.ORCID http://orcid.org/0000-0001-6886-5156
Syudo YamasakiResearch Center for Social Science & Medicine, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Shuntaro AndoDepartment of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Kaori EndoResearch Center for Social Science & Medicine, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Yuko MorimotoDepartment of Psychology, Ube Frontier University, Ube, Japan.
Sho KanataDepartment of Psychiatry, Teikyo University School of Medicine, Tokyo, Japan.
Shinya FujikawaDepartment of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Noriko CableDepartment of Epidemiology and Public Health, University College London, London, UK.
Hiroyasu IsoInstitute for Global Health Policy Research, Bureau of International Health Cooperation, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan.
Mariko Hiraiwa-HasegawaDepartment of Evolutionary Studies of Biosystems, The Graduate University for the Advanced Studies, SOKENDAI, Hayama, Japan.
Kiyoto KasaiDepartment of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Atsushi NishidaResearch Center for Social Science & Medicine, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
The University of Tokyo · JPTokyo Metropolitan Institute of Medical Science · JPJuntendo University · JPNational Center for Global Health and Medicine · JPTeikyo University · JPThe Graduate University for Advanced Studies, SOKENDAI · JPUbe Frontier University · JPUniversity College London · GB

Funding

Japan Society for the Promotion of Science JP16H06395Japan Society for the Promotion of Science JP16H06399Japan Society for the Promotion of Science JP16K21720Japan Society for the Promotion of Science JP19H04877Japan Society for the Promotion of Science JP21K10487
6 · The paper itself

Abstract

Adolescents with high autistic traits are at increased risk of depression. Despite the importance of seeking help for early intervention, evidence on help-seeking intentions amongst this population is scarce. Using a population-based cohort in Japan, we examined adolescents' help-seeking intentions and preferences by the level of autistic traits and tested its mediating role on the association between high autistic traits and depressive symptoms. At age 12, we measured parent-rated autistic traits using the short version of the Autism Spectrum Quotient and classified the adolescents into two groups (≥ 6 as AQhigh, < 6 as AQlow); help-seeking intentions and preferences were assessed through a depression vignette. At age 14, depressive symptoms were self-rated using the Short Mood and Feelings Questionnaire. Hypothesised associations between autistic traits and help-seeking intentions or depressive symptoms were tested applying multivariable regression modelling, while mediation was tested with structural equation modelling. Of the 2505 adolescent participants, 200 (8%) were classified as AQhigh. In both groups, the main source of help-seeking was their family; however, 40% of the AQhigh group reported having no help-seeking intentions compared to 27% in the AQlow. The AQhigh group was at increased risk of not having help-seeking intentions (OR 1.84, 95% CI 1.35-2.50) and higher depressive symptoms (b coefficient 1.06, 0.33-1.79). Help-seeking intentions mediated 18% of the association mentioned above. Interventions to promote help-seeking intentions among adolescents with high autistic traits could reduce their subsequent depressive symptoms. Ideally, such interventions should be provided prior to adolescence and with the involvement of their parents.

Indexed as

Autistic DisorderDepressionAdolescentChildCohort StudiesHumansIntentionSurveys and QuestionnairesAdolescenceAutistic traitsDepressionHelp-seekingPopulation-based study

Identifiers

PMID34694472
PMCPMC10115668
OpenAlexW3209632492

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.