ArticleBlood transfusion = Trasfusione del sangue2022
Vasovagal reactions in whole blood and apheresis donors: a cross-sectional study on donor haemovigilance data from 2016 to 2019 in Italy.
Article in Blood transfusion = Trasfusione del sangue, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.
- Artificial Intelligence-based predictive models for adverse blood donor reactions: a systematic review of immediate and delayed events and clinical data approaches.BMC medical informatics and decision making · 2026Pooled it
- Risk factors for vasovagal reactions in blood donors: A systematic review and meta-analysis.Transfusion · 2025Pooled it
- Evaluating blood donation safety for donors with sickle cell trait.Vox sanguinis · 2026Article
- Onsite vasovagal reactions with and without loss of consciousness are distinct outcomes with different risk factors.Vox sanguinis · 2025Article
- Article
- Application of predonation hydration for vasovagal reactions during blood donation: a bibliometric analysis (2004-2023).Frontiers in medicine · 2025Article
- Profile and risk factors of blood donors who experienced adverse reactions: a cross-sectional study on donor hemovigilance data reported to the national network from 2020 to 2022 in China.Frontiers in public health · 2025Article
- Sociodemographic Factors Related to Adverse Donor Reactions in Shenzhen.International journal of general medicine · 2023Article
- Novel risk patterns of vasovagal reactions in NZ blood donations complicated by COVID-19 restrictions.Frontiers in public health · 2023Article
- Delayed Vasovagal Reaction with Reflex Syncope Following COVID-19 Vaccination.Internal medicine (Tokyo, Japan) · 2022Article
- Feline blood donation: Description and adverse reactions from 29 201 donation events between 2019 and 2023.Journal of veterinary internal medicineArticle
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute and delayed vasovagal reactions (VVR) are the most frequent adverse reactions (AR) associated with donations. The aim of this study was to provide the data of the Italian donor haemovigilance system and contextualise the VVR data within the international framework, as well as evaluating, among first-time donors, the association of gender and age and the prevalence of VVR compared to other AR. MATERIALS AND
methodsThe prevalence analysis was performed on VVR and other AR notified to the Italian haemovigilance system from 2016 to 2019. The analysis on the association of gender and age group and VVR prevalence was performed on first-time donations. The definitions and severity of AR were as set out in the 2014 ISBT/IHN international standards.
resultsFrom 2016 to 2019, 34,519 AR were notified, of which 87.1% were VVR. The overall VVR prevalence was 25.0/10,000 donations and the overall prevalence of other AR was 3.7/10,000 donations. All the estimated prevalences of AR were higher for first-time donations than for regular donations and lower for whole blood than for apheresis donations. No difference was noted between whole blood and apheresis donations for VVR with complications or injuries. The prevalence of AR among first-time donors was higher in females than in males. The prevalence of VVR decreased as donor age increased. DISCUSSION: The prevalence of VVR related to blood donation was very low and similar to those calculated by other haemovigilance systems. Among first-time donors, the prevalence of AR was higher in females than in males. The higher prevalence of VVR in young donors and a significant decreasing trend by age group confirmed the results reported in the literature. Finally, no trend by age group in first-time donors was observed for other AR to donations.
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