Evidence map›Paper›PMID 34693655›Full record

ArticleObesity (Silver Spring, Md.)2021

Obesity and cancer death in white and black adults: A prospective cohort study.

Justin C Brown, Shengping Yang, Emily F Mire, Xiaocheng Wu, Lucio Miele, Augusto Ochoa, Jovanny Zabaleta, Peter T Katzmarzyk

Registry-linked trialAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00959270 (Pennington Center Longitudinal), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00959270 recruitingnot on this map

Pennington Center Longitudinal (PCLS)

TypeobservationalSponsorPennington Biomedical Research CenterRan2009 to 2050Enrolled30,000ConditionsHealth Behaviors, Development of Health Problems
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Ranking of Health Problems and Prioritization of Cancer Education Topics by African American Communities in South Carolina.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025
    Article
  2. Association of Abdominal Visceral Adiposity and Total Fat Mass with Cancer Incidence and Mortality in White and Black Adults.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Justin C BrownPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.ORCID 0000-0001-7540-4913
Shengping YangPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Emily F MirePennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Xiaocheng WuSchool of Medicine, LSU Health New Orleans, New Orleans, Louisiana, USA.
Lucio MieleSchool of Medicine, LSU Health New Orleans, New Orleans, Louisiana, USA.
Augusto OchoaSchool of Medicine, LSU Health New Orleans, New Orleans, Louisiana, USA.
Jovanny ZabaletaSchool of Medicine, LSU Health New Orleans, New Orleans, Louisiana, USA.
Peter T KatzmarzykPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.ORCID 0000-0002-9280-6022

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Leigh Lamonica · 2012 to 2026
$69.1M
Research BaseP30DK072476 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Eric Ravussin · 2005 to 2026
$26.5M
Understanding and Addressing Cancer Health Disparities in LouisianaP20CA233374 · NCI · LSU HEALTH SCIENCES CENTER · PI MIELE, LUCIO · 2018 to 2020
$2.9M
Transdisciplinary Research in Energetics and Cancer (TREC) Training GrantR25CA203650 · NCI · YALE UNIVERSITY · PI IRWIN, MELINDA L · 2016 to 2025
$2.9M
Inflammation, Physical Activity, and Colon Cancer Recurrence and SurvivalR00CA218603 · NCI · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI BROWN, JUSTIN C · 2019 to 2021
$747k
NCI NIH HHS P20 CA233374NCI NIH HHS R00 CA218603NCI NIH HHS R00-CA218603NCI NIH HHS R25 CA203650NCI NIH HHS R25-CA203650NIDDK NIH HHS P30 DK072476NIDDK NIH HHS P30-DK072476NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

objectiveThis study aimed to determine whether race modifies the association between obesity and cancer death.

methodsThe Pennington Center Longitudinal Study included 18,296 adults; 35.0% were male and 34.3% were Black. The primary end point was death from cancer.

resultsDuring a follow-up of 14.3 years, 346 cancer deaths occurred. Among men, race modified the association of BMI and cancer death (p

conclusionsIn this diverse cohort of adults, having obesity was associated with an increased risk of cancer death in White men and women. In contrast, having obesity was associated with a reduced risk of cancer death in Black men and did not influence risk in Black women.

Indexed as

NeoplasmsWhite PeopleAdultBlack or African AmericanBody Mass IndexCohort StudiesFemaleHumansLongitudinal StudiesMaleObesityProspective StudiesRisk Factors

Identifiers

PMID34693655
PMCPMC9256081

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.