Evidence map›Paper›PMID 34693586›Full record

ArticleJournal of paediatrics and child health2022

Characteristics and outcomes of SARS-CoV-2 infection in Victorian children at a tertiary paediatric hospital.

Shidan Tosif, Laila F Ibrahim, Rebecca Hughes, Daryl R Cheng, Danielle Wurzel, Isabella Overmars, Andrew C Steer, Penelope A Bryant, Trevor Duke, Stuart Lewena and 3 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of paediatrics and child health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Shidan TosifDepartment of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0003-0022-1009
Laila F IbrahimDepartment of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.
Rebecca HughesDepartments of General Medicine, The Royal Children's Hospital, Melbourne, Victoria, Australia.
Daryl R ChengDepartment of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0001-5455-957X
Danielle WurzelDepartment of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0003-2917-2773
Isabella OvermarsInfection and Immunity, Murdoch Children 's Research Institute, Melbourne, Victoria, Australia.ORCID 0000-0002-9710-6113
Andrew C SteerDepartment of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.
Penelope A BryantDepartment of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.
Trevor DukeDepartment of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0003-4637-1416
Stuart LewenaDepartment of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.
Franz E BablDepartment of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0002-1107-2187
Sarah McNabDepartment of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.
Nigel CrawfordDepartment of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.
Royal Children's Hospital · AUMurdoch Children's Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimVictoria experienced two 'waves' of COVID-19 between March and September 2020 and more cases than any other jurisdiction in Australia. Although world-wide reports of COVID-19 reflect that children are less likely to experience severe disease compared with adults, hospitalisations and deaths have been reported. We report testing and outcomes of children with SARS-CoV-2 infection presenting to a tertiary paediatric hospital in Melbourne.

methodsWe conducted a prospective cohort study at The Royal Children's Hospital (RCH), including all children and adolescents (aged 0-18 years) who presented and were tested for SARS-CoV-2 over a 6-month period, between 21 March 2020, up to the 21 September 2020. Detailed epidemiological and clinical data were recorded.

resultsA total of 19 708 tests for SARS-CoV-2 were performed in 14 419 patients. One hundred and eighty patients tested positive for SARS-CoV-2 (1.2%). 110 (61%) were symptomatic, 60 (33%) were asymptomatic and 10 (6%) were pre-symptomatic. Close contacts of a positive case were associated with a higher risk of a testing positive for SARS-CoV-2 (120/2027 (6%) vs. 60/14589 (0.4%), RD 5.5 (95% CI 4.5 to 6.5), P < 0.001). Eighteen (10%) SARS-CoV-2-positive patients were admitted to hospital with one patient requiring intensive care. All patients recovered fully with no deaths.

conclusionIn Victorian children presenting to a tertiary hospital, SARS-CoV-2 infection caused predominantly mild or asymptomatic infection, with most children not requiring hospitalisation.

Indexed as

COVID-19AdolescentAdultChildChild, PreschoolHospitals, PediatricHumansInfantInfant, NewbornProspective StudiesSARS-CoV-2Tertiary Care CentersVictoriaCOVID-19general paediatricsinfectious disease

Identifiers

PMID34693586
PMCPMC8662161
OpenAlexW3208065270

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.