Evidence map›Paper›PMID 34693544›Full record

ArticleAndrologia2022

SARS-CoV-2 is not found in human semen during mild COVID-19 acute stage.

Renato Fraietta, Renata Cristina de Carvalho, Jacqueline Camillo, Matheus Ferreira Groner, José Carlos Cezar Ibanhez Truzzi, Camila Nogueira Petkov, Valéria Barradas, Carolina Homsi, Nancy Bellei, Sergio Oehninger

Abstract read
In one paragraph

Article in Andrologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Urological complications of COVID-19: a systematic review.International braz j urol : official journal of the Brazilian Society of Urology
    Pooled it
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. SARS-CoV-2, fertility and assisted reproduction.Human reproduction update · 2023
    Review
  11. COVID-19 vaccination does not affect male sexual functions.Reproductive biology and endocrinology : RB&E · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Renato FraiettaDivision of Urology, Department of Surgery, Sao Paulo Federal University - UNIFESP, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-6491-7788
Renata Cristina de CarvalhoDivision of Urology, Department of Surgery, Sao Paulo Federal University - UNIFESP, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-2284-803X
Jacqueline CamilloDivision of Urology, Department of Surgery, Sao Paulo Federal University - UNIFESP, São Paulo, Brazil.
Matheus Ferreira GronerDivision of Urology, Department of Surgery, Sao Paulo Federal University - UNIFESP, São Paulo, Brazil.
José Carlos Cezar Ibanhez TruzziStudent Health Service (Urology), Sao Paulo Federal University - UNIFESP, São Paulo, Brazil.
Camila Nogueira PetkovDivision of Urology, Department of Surgery, Sao Paulo Federal University - UNIFESP, São Paulo, Brazil.
Valéria BarradasDivision of Urology, Department of Surgery, Sao Paulo Federal University - UNIFESP, São Paulo, Brazil.
Carolina HomsiDivision of Urology, Department of Surgery, Sao Paulo Federal University - UNIFESP, São Paulo, Brazil.
Nancy BelleiVirology Laboratory, Department of Medicine, Sao Paulo Federal University -UNIFESP, São Paulo, Brazil.
Sergio OehningerReproductive Biology Unit, University of Stellenbosch, Stellenbosch, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to verify the presence of SARS-CoV-2 in the seminal sample of men during the acute phase of COVID-19. A prospective study was performed with inclusion of twenty-two men diagnosed with COVID-19 through RT-PCR from pharyngeal smear samples and who were in the acute phase of infection. These men were evaluated regarding medical history and physical examination. Furthermore, seminal samples of each men were collected 7, 14 and 21 days after the infection was confirmed. The sample were used for seminal analysis, as well as for the presence of SARS-CoV-2 using RT-PCR technique. In addition, cell culture was performed with subsequent repetition of the analysis of viral presence. None of the semen samples collected was positive for the detection of the virus that causes COVID-19. Most of the men evaluated had a mild condition and the loss of smell was the most frequent symptom. There were no significant changes in seminal parameters within the period of study. Based on our pilot data, patients with a mild form of COVID-19 in the acute stage of the disease are unlikely to have SARS-CoV-2 in semen.

Indexed as

COVID-19SARS-CoV-2HumansMaleProspective StudiesRNA, ViralSemenRNA, ViralCOVID-19SARS-CoV-2semenviruses

Identifiers

PMID34693544
PMCPMC8646908

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.