Evidence map›Paper›PMID 34693396›Full record

ArticleIBRO neuroscience reports2021

Altered neural networks and cognition in a hereditary colon cancer.

Ryan J Cali, Benjamin C Nephew, Constance M Moore, Serhiy Chumachenko, Ana Cecilia Sala, Beatriz Cintron, Carlos Luciano, Jean A King, Stephen R Hooper, Francis M Giardiello and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in IBRO neuroscience reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. APC in the nervous system.Medical molecular morphology · 2026
    Review
  3. Mapping Cognitive Oncology: A Decade of Trends and Research Fronts.Medical sciences (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Ryan J CaliDepartment of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Benjamin C NephewDepartment of Psychiatry, UMass Medical School, Worcester, MA, USA.
Constance M MooreDepartment of Psychiatry, UMass Medical School, Worcester, MA, USA.
Serhiy ChumachenkoDepartment of Psychiatry, UMass Medical School, Worcester, MA, USA.
Ana Cecilia SalaDepartment of Medicine, Medical Sciences Campus, University of Puerto Rico School of Medicine, San Juan, PR, USA.
Beatriz CintronDepartment of Medicine, Medical Sciences Campus, University of Puerto Rico School of Medicine, San Juan, PR, USA.
Carlos LucianoDepartment of Medicine, Medical Sciences Campus, University of Puerto Rico School of Medicine, San Juan, PR, USA.
Jean A KingDepartment of Psychiatry, UMass Medical School, Worcester, MA, USA.
Stephen R HooperDepartment of Allied Health Sciences, School of Medicine, University of North Carolina-Chapel Hill, NC, USA.
Francis M GiardielloDivision of Gastroenterology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Marcia Cruz-CorreaDepartment of Medicine, Medical Sciences Campus, University of Puerto Rico School of Medicine, San Juan, PR, USA.
University of Massachusetts Chan Medical School · USUniversity of Puerto Rico, Medical Sciences Campus · PRJohns Hopkins Medicine · USMassachusetts General Hospital · USUniversity of North Carolina at Chapel Hill · US

Funding

Tracking and Evaluation CoreU54GM133807 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI BONILLA-FELIX, MELVIN · 2020 to 2024
$17.7M
NIGMS NIH HHS U54 GM133807
6 · The paper itself

Abstract

Familial Adenomatous Polyposis (FAP) is an autosomal dominant disorder caused by mutation of the

Indexed as

CancerCognitionFamilial Adenomatous PolyposisfMRINeural networksResting state functional connectivity

Identifiers

PMID34693396
PMCPMC8517154
OpenAlexW3202190901

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.