Evidence map›Paper›PMID 34693255›Full record

ArticleKidney medicine

Association of Self-Rated Health With Functional Limitations in Patients With CKD.

Jacqueline Lee, Khaled Abdel-Kader, Jonathan G Yabes, Manqi Cai, Hsin-Hsiung Chang, Manisha Jhamb

Open access · goldAbstract read
In one paragraph

Article in Kidney medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Baseline characteristics of participants in the NAVKIDSPediatric nephrology (Berlin, Germany) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jacqueline LeeDepartment of Medicine, School of Medicine, Pittsburgh, PA.
Khaled Abdel-KaderVanderbilt University, Nephrology and Hypertension Division, Nashville, TN.
Jonathan G YabesCenter for Research on Health Care, Division of General Internal Medicine, Pittsburgh, PA.
Manqi CaiDepartment of Biostatistics, University of Pittsburgh, Pittsburgh, PA.
Hsin-Hsiung ChangDivision of Nephrology, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan.
Manisha JhambRenal-Electrolyte Division, Pittsburgh, PA.
University of Pittsburgh · USChanghua Christian Hospital · TWVanderbilt University · US

Funding

Single Nephron and MetabolomicsP30DK079307 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2008 to 2022
$13.4M
NIDDK NIH HHS P30 DK079307
6 · The paper itself

Abstract

RATIONALE &

objectiveIn patients with chronic kidney disease (CKD), self-rated health ("In general, how do you rate your health?") is associated with mortality. The association of self-rated health with functional status is unknown. We evaluated the association of limitations in activities of daily living (ADLs) with self-rated health and clinical correlates in a cohort of patients with CKD stages 1-5. STUDY

designProspective cohort study. SETTING &

participantsPatients with CKD at a nephrology outpatient clinic in western Pennsylvania. OUTCOME: Patients participated in a survey assessing their self-rated health (5-point Likert scale) and physical (ambulation, dressing, shopping) and cognitive (executive and memory) ADLs. Adjusted analysis was performed using logistic regression models. ANALYTICAL APPROACH: Logistic regression was conducted to examine the adjusted association of 3 dependent variables (sum of total, physical, and cognitive ADL limitations) with self-rated health (independent variable of interest).

resultsThe survey was completed by 1,268 participants (mean age, 60 years; 49% females, and 74% CKD stages 3-5), of which 41% reported poor-to-fair health. Overall, 35.9% had at least 1 physical ADL limitation, 22.1% had at least 1 cognitive ADL limitation, and 12.5% had at least 3 ADL limitations. Ambulation was the most frequently reported limitation and was more common in patients reporting poor-to-fair self-rated health compared with those with good-to-excellent self-rated health (58.1% vs 17.4%, LIMITATIONS: Selection bias due to optional survey completion, residual confounding, and use of abbreviated (as opposed to full) ADL questionnaires.

conclusionsPoor-to-fair self-rated health is strongly associated with physical ADL limitations in patients with CKD. Future studies should evaluate whether self-rated health questions may be useful for identifying patients who can benefit from additional evaluation and treatment of functional limitations to improve patient-centered outcomes.

Indexed as

Ambulationchronic kidney diseasecognitive functionexecutive functionfunctional statusinstrumental activities of daily livinglimitations in activities of daily livingquality of lifeself-rated health

Identifiers

PMID34693255
PMCPMC8515078
OpenAlexW3177276792

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.