Evidence map›Paper›PMID 34693075›Full record

ArticleCurrent opinion in endocrine and metabolic research2021

Control of ovarian follicle development by TGFβ family signaling.

Bethany K Patton, Surabhi Madadi, Stephanie A Pangas

Open access · greenAbstract read
In one paragraph

Article in Current opinion in endocrine and metabolic research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
9.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
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  6. Expression ofInternational journal of reproductive biomedicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Bethany K PattonDepartment of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.
Surabhi MadadiRice University, 6100 Main St, Houston, TX 77005.
Stephanie A PangasDepartment of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030.
Baylor College of Medicine · USRice University · US

Funding

Comprehensive Mechanisms in Reproductive SciencesT32HD098068 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI STEPHANIE A. PANGAS · 2020 to 2026
$2.4M
Protein Sumoylation in OOCYTE DevelopmentR01HD085994 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI PANGAS, STEPHANIE A. · 2017 to 2021
$1.6M
NICHD NIH HHS R01 HD085994NICHD NIH HHS T32 HD098068
6 · The paper itself

Abstract

The reproductive lifespan of female mammals is limited and ultimately depends on the production of a sufficient number of high quality oocytes from a pool of non-growing primordial follicles that are set aside during embryonic and perinatal development. Recent studies show multiple signaling pathways are responsible for maintaining primordial follicle arrest and regulation of activation. Identification of these pathways and their regulatory mechanisms is essential for developing novel treatments for female infertility, improving existing

Indexed as

folliculogenesisgrowth factorsinfertilityreproduction

Identifiers

PMID34693075
PMCPMC8535782
OpenAlexW3138591064

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.