Evidence map›Paper›PMID 34692849›Full record

ArticleJournal of diabetes research2021

Study on the Mechanism of Prunella Vulgaris L on Diabetes Mellitus Complicated with Hypertension Based on Network Pharmacology and Molecular Docking Analyses.

Xinyi Jiao, Haiying Liu, Qinan Lu, Yu Wang, Yue Zhao, Xuemei Liu, Fang Liu, Yaoyao Zuo, Wenbo Wang, Yujie Li

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Water-ExtractedFrontiers in pharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Xinyi JiaoCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.ORCID https://orcid.org/0000-0001-5618-8223
Haiying LiuChaYeKou Town Health Center of LaiWu District, Jinan, China.
Qinan LuThe Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Yu WangThe Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Yue ZhaoThe Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Xuemei LiuThe Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Fang LiuThe Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Yaoyao ZuoThe Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Wenbo WangThe Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.ORCID https://orcid.org/0000-0002-2982-4199
Yujie LiThe Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.ORCID https://orcid.org/0000-0002-6249-2237
Shandong University of Traditional Chinese Medicine · CNJinan City People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of traditional Chinese medicine Prunella vulagaris L in the treatment of tumors and inflammation has been widely confirmed. We found that some signaling pathways of Prunella vulgaris L action can also regulate diabetes and hypertension, so we decided to study the active ingredients, potential targets and signaling pathway of Prunrlla vulgaris L, and explore the "multi-target, multi-pathway" molecular mechanism of Prunella vulgaris L on diabetes mellitus complicated with hypertension(DH).

Indexed as

PrunellaDiabetes MellitusDrugs, Chinese HerbalFlavonoidsGlycation End Products, AdvancedHumansHypertensionInsulinInterleukin-6MAP Kinase Signaling SystemMolecular Docking SimulationNetwork PharmacologyPhosphatidylinositol 3-KinasesPhytosterolsProtein Interaction MapsProto-Oncogene Proteins c-aktDrugs, Chinese HerbalFlavonoidsGlycation End Products, AdvancedInsulinInterleukin-6Phosphatidylinositol 3-KinasesPhytosterolsProto-Oncogene Proteins c-aktQuercetinReceptor for Advanced Glycation End ProductsTumor Necrosis Factor-alpha

Identifiers

PMID34692849
PMCPMC8536441
OpenAlexW3205637211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.