Evidence map›Paper›PMID 34692842›Full record

Trial reportBioMed research international2021

Effect of Prepregnancy Lymphocyte Active Immunotherapy on Unexplained Recurrent Miscarriage, Pregnancy Success Rate, and Maternal-Infant Outcome.

Junxia Li, Yan Gu, Shaojing Zhang, Baohui Ju, Jianmei Wang

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Junxia LiDepartment of Obstetrics and Gynecology, Second Hospital Affiliated to Tianjin Medical University, China.
Yan GuDepartment of Obstetrics and Gynecology, Second Hospital Affiliated to Tianjin Medical University, China.
Shaojing ZhangDepartment of Obstetrics and Gynecology, Second Hospital Affiliated to Tianjin Medical University, China.
Baohui JuDepartment of Obstetrics and Gynecology, Second Hospital Affiliated to Tianjin Medical University, China.
Jianmei WangDepartment of Obstetrics and Gynecology, Second Hospital Affiliated to Tianjin Medical University, China.ORCID https://orcid.org/0000-0003-2811-4344
Second Hospital of Tianjin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effect of prepregnancy lymphocyte active immunotherapy on unexplained recurrent miscarriage, pregnancy success rate, and maternal-infant outcome.

methodsA total of 124 patients with recurrent miscarriage admitted to our hospital from January 2018 to December 2020 were selected as the research objects and divided into the experimental group and the control group according to the random number table method, with 62 patients in each group. The experimental group was treated with lymphocyte active immunotherapy, and the control group was given conventional treatment. The pregnancy success rate, estrogen indexes, hemorheology indexes, and psychological state of the two groups were compared.

resultsThe experimental group garnered a notably higher pregnancy success rate and a prominently lower miscarriage rate than the control group (

conclusionThe use of lymphocyte active immunotherapy for patients with unexplained recurrent miscarriage can significantly increase the pregnancy success rate, optimize the maternal-infant outcome, drive down the miscarriage rate, and ameliorate the patient's estrogen levels and hemorheology indicators, which is worthy of promotion and application in clinical practice.

Indexed as

Abortion, HabitualAdultCase-Control StudiesFemaleHumansImmunotherapy, ActiveImmunotherapy, AdoptiveInfantLymphocyte ActivationLymphocytesLymphocyte TransfusionMaleMother-Child RelationsPregnancyPregnancy OutcomePregnancy RateProgesterone

Identifiers

PMID34692842
PMCPMC8531784
OpenAlexW3207897909

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.