Evidence map›Paper›PMID 34692789›Full record

ArticleFrontiers in cardiovascular medicine2021

A Novel Endothelial Damage Inhibitor Reduces Oxidative Stress and Improves Cellular Integrity in Radial Artery Grafts for Coronary Artery Bypass.

Thomas Aschacher, Ulrike Baranyi, Olivia Aschacher, Eva Eichmair, Barbara Messner, Daniel Zimpfer, Roxana Moayedifar, Guenther Laufer, Maximilian Y Emmert, Sigrid E Sandner

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

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  9. Outcomes after surgical revascularization in diabetic patients.Interdisciplinary cardiovascular and thoracic surgery · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Thomas AschacherDepartment of Cardio-Vascular Surgery, Clinic Floridsdorf and Karl Landsteiner Institute for Cardio-Vascular Research, Vienna, Austria.
Ulrike BaranyiDepartment of Cardiac Surgery, Medical University Vienna, Vienna, Austria.
Olivia AschacherDepartment of Plastic, Reconstructive and Plastic Surgery, Medical University Vienna, Vienna, Austria.
Eva EichmairDepartment of Cardiac Surgery, Medical University Vienna, Vienna, Austria.
Barbara MessnerDepartment of Cardiac Surgery, Medical University Vienna, Vienna, Austria.
Daniel ZimpferDepartment of Cardiac Surgery, Medical University Vienna, Vienna, Austria.
Roxana MoayedifarDepartment of Cardiac Surgery, Medical University Vienna, Vienna, Austria.
Guenther LauferDepartment of Cardiac Surgery, Medical University Vienna, Vienna, Austria.
Maximilian Y EmmertCardiovascular Surgery, Charite-Universitätsmedizin Berlin, Berlin, Germany.
Sigrid E SandnerDepartment of Cardiac Surgery, Medical University Vienna, Vienna, Austria.
Medical University of Vienna · ATCharité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The radial artery (RA) is a frequently used conduit in coronary artery bypass grafting (CABG). Endothelial injury incurred during graft harvesting promotes oxidative damage, which leads to graft disease and graft failure. We evaluated the protective effect of DuraGraft®, an endothelial damage inhibitor (EDI), on RA grafts. We further compared the protective effect of the EDI between RA grafts and saphenous vein grafts (SVG). Samples of RA (

Indexed as

bypass graft failurecoronary artery bypass graftingendothelial damage inhibitoroxidative damageradial artery

Identifiers

PMID34692789
PMCPMC8527012
OpenAlexW3203266479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.