Evidence map›Paper›PMID 34692743›Full record

ReviewFrontiers in nutrition2021

Biofortification of Cereals and Pulses Using New Breeding Techniques: Current and Future Perspectives.

Rahil Shahzad, Shakra Jamil, Shakeel Ahmad, Amina Nisar, Sipper Khan, Zarmaha Amina, Shamsa Kanwal, Hafiz Muhammad Usman Aslam, Rafaqat Ali Gill, Weijun Zhou

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
10.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 77 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Biofortification of Mushrooms: A Promising Approach.Molecules (Basel, Switzerland) · 2024
    Review
  6. Review
  7. Review
  8. Review
  9. 3Bs of CRISPR-Cas mediated genome editing in plants: exploring the basics, bioinformatics and biosafety landscape.Physiology and molecular biology of plants : an international journal of functional plant biology · 2023
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Rahil ShahzadAgricultural Biotechnology Research Institute, Ayub Agricultural Research Institute, Faisalabad, Pakistan.
Shakra JamilAgricultural Biotechnology Research Institute, Ayub Agricultural Research Institute, Faisalabad, Pakistan.
Shakeel AhmadMaize Research Station, Ayub Agricultural Research Institute, Faisalabad, Pakistan.
Amina NisarDepartment of Plant Breeding and Genetics, University of Agriculture, Faisalabad, Pakistan.
Sipper KhanTropics and Subtropics Group, Institute of Agricultural Engineering, University of Hohenheim, Stuttgart, Germany.
Zarmaha AminaTropics and Subtropics Group, Institute of Agricultural Engineering, University of Hohenheim, Stuttgart, Germany.
Shamsa KanwalAgricultural Biotechnology Research Institute, Ayub Agricultural Research Institute, Faisalabad, Pakistan.
Hafiz Muhammad Usman AslamInstitute of Plant Protection, Muhammad Nawaz Sharif University of Agriculture, Multan, Pakistan.
Rafaqat Ali GillKey Laboratory of Biology and Genetic Improvement of Oil Crops, The Ministry of Agriculture and Rural Affairs, Oil Crops Research Institute of Chinese Academy of Agricultural Sciences, Wuhan, China.
Weijun ZhouKey Laboratory of Spectroscopy Sensing, The Ministry of Agriculture and Rural Affairs, Institute of Crop Science, Zhejiang University, Hangzhou, China.
Ayub Agriculture Research Institute · PKUniversity of Hohenheim · DEMinistry of Agriculture and Rural Affairs · CNMuhammad Nawaz Shareef University of Agriculture · PKUniversity of Agriculture Faisalabad · PKZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cereals and pulses are consumed as a staple food in low-income countries for the fulfillment of daily dietary requirements and as a source of micronutrients. However, they are failing to offer balanced nutrition due to deficiencies of some essential compounds, macronutrients, and micronutrients, i.e., cereals are deficient in iron, zinc, some essential amino acids, and quality proteins. Meanwhile, the pulses are rich in anti-nutrient compounds that restrict the bioavailability of micronutrients. As a result, the population is suffering from malnutrition and resultantly different diseases, i.e., anemia, beriberi, pellagra, night blindness, rickets, and scurvy are common in the society. These facts highlight the need for the biofortification of cereals and pulses for the provision of balanced diets to masses and reduction of malnutrition. Biofortification of crops may be achieved through conventional approaches or new breeding techniques (NBTs). Conventional approaches for biofortification cover mineral fertilization through foliar or soil application, microbe-mediated enhanced uptake of nutrients, and conventional crossing of plants to obtain the desired combination of genes for balanced nutrient uptake and bioavailability. Whereas, NBTs rely on gene silencing, gene editing, overexpression, and gene transfer from other species for the acquisition of balanced nutritional profiles in mutant plants. Thus, we have highlighted the significance of conventional and NBTs for the biofortification of cereals and pulses. Current and future perspectives and opportunities are also discussed. Further, the regulatory aspects of newly developed biofortified transgenic and/or non-transgenic crop varieties

Indexed as

anti-nutrientsconventional breedingCRISPR-Casfertilizationgenome editingmalnutritionmicronutrientstransgenic breeding

Identifiers

PMID34692743
PMCPMC8528959
OpenAlexW3207340222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.