Evidence map›Paper›PMID 34692725›Full record

ArticleFrontiers in medicine2021

PNPLA3, TM6SF2, and MBOAT7 Influence on Nutraceutical Therapy Response for Non-alcoholic Fatty Liver Disease: A Randomized Controlled Trial.

Marcello Dallio, Mario Masarone, Mario Romeo, Concetta Tuccillo, Filomena Morisco, Marcello Persico, Carmelina Loguercio, Alessandro Federico

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Frontiers in oncology · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. NAFLD and NAFLD Related HCC: Emerging Treatments and Clinical Trials.International journal of molecular sciences · 2025
    Review
  12. Silybin A fromTheranostics · 2025
    Article
  13. Review
  14. Current Therapeutical Approaches Targeting Lipid Metabolism in NAFLD.International journal of molecular sciences · 2023
    Review
  15. Review
  16. Microbiota-Liver Diseases Interactions.International journal of molecular sciences · 2023
    Review
  17. Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Marcello DallioDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Mario MasaroneDepartment of Medicine and Surgery, University of Salerno, Salerno, Italy.
Mario RomeoDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Concetta TuccilloDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Filomena MoriscoDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Marcello PersicoDepartment of Medicine and Surgery, University of Salerno, Salerno, Italy.
Carmelina LoguercioDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Alessandro FedericoDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
University of Campania "Luigi Vanvitelli" · ITUniversity of Salerno · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

geneticsgenome wide association studiesinsulin resistancenutraceuticssystemic inflammation

Identifiers

PMID34692725
PMCPMC8531439
OpenAlexW3207850867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.