Evidence map›Paper›PMID 34692682›Full record

ArticleFrontiers in cell and developmental biology2021

Glucocorticoid-Responsive Transcription Factor Krüppel-Like Factor 9 Regulates

Ian M Gans, Janelle Grendler, Remy Babich, Nishad Jayasundara, James A Coffman

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ian M GansMDI Biological Laboratory, Bar Harbor, ME, United States.
Janelle GrendlerMDI Biological Laboratory, Bar Harbor, ME, United States.
Remy BabichThe School of Marine Sciences, University of Maine, Orono, ME, United States.
Nishad JayasundaraNicholas School of the Environment, Duke University, Durham, NC, United States.
James A CoffmanMDI Biological Laboratory, Bar Harbor, ME, United States.
University of Maine · USDuke University · USMount Desert Island Biological Laboratory · US

Funding

The Maine Biomedical Research Network (INBRE)P20GM103423 · NIGMS · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI Dustin Lynn Updike · 2012 to 2026
$60.0M
Gene regulatory circuitry underlying the dynamic control of glucocorticoid signalingR03HD099468 · NICHD · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI COFFMAN, JAMES A · 2019 to 2020
$166k
NICHD NIH HHS R03 HD099468NIGMS NIH HHS P20 GM103423
6 · The paper itself

Abstract

Krüppel-like factor 9 (Klf9) is a feedforward regulator of glucocorticoid receptor (GR) signaling. Here we show that in zebrafish

Indexed as

cortisolfkbp5gene expressionglucocorticoid receptorKrüppel-like factor 9metabolismRNA-seqzebrafish

Identifiers

PMID34692682
PMCPMC8526736
OpenAlexW3204161755

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.