Evidence map›Paper›PMID 34692671›Full record

ArticleFrontiers in cell and developmental biology2021

Bone Morphogenetic Protein 4 Alleviates DSS-Induced Ulcerative Colitis Through Activating Intestinal Stem Cell by Target ID3.

Lei Hu, Junji Xu, Xue Wang, Liang Feng, Chunmei Zhang, Jinsong Wang, Songlin Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

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  8. Dysregulation of CD4Journal for immunotherapy of cancer · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lei HuSalivary Gland Disease Center, Capital Medical University School of Stomatology, Beijing, China.
Junji XuSalivary Gland Disease Center, Capital Medical University School of Stomatology, Beijing, China.
Xue WangSalivary Gland Disease Center, Capital Medical University School of Stomatology, Beijing, China.
Liang FengSalivary Gland Disease Center, Capital Medical University School of Stomatology, Beijing, China.
Chunmei ZhangSalivary Gland Disease Center, Capital Medical University School of Stomatology, Beijing, China.
Jinsong WangBeijing Laboratory of Oral Health, Capital Medical University, Beijing, China.
Songlin WangBeijing Laboratory of Oral Health, Capital Medical University, Beijing, China.
Capital Medical University · CNBeijing Friendship Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Damage to intestinal epithelial cell proliferation or intestinal stem cell (ISC) maintenance may trigger inflammatory bowel disease (IBD), and protecting the ISCs is critical for IBD treatment. Here, we found that in the dextran sulfate sodium (DSS)-induced ulcerative colitis mice model, colon epithelium and Lgr5

Indexed as

BMP4epithelium proliferationID3intestinal stem cellulcerative colitis

Identifiers

PMID34692671
PMCPMC8528200
OpenAlexW3204669548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.