Evidence map›Paper›PMID 34692667›Full record

ArticleFrontiers in bioengineering and biotechnology2021

Development of A Decahedral Nanoenzyme Capable of Overcoming Hypoxia to Facilitate the Iodine-125 Radiosensitization of Esophageal Cancer.

Dechao Jiao, Kunpeng Wu, Kaihao Xu, Yiming Liu, Deyao Zhao, Xinwei Han, Ruitai Fan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Dechao JiaoDepartment of Interventional Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Kunpeng WuDepartment of Interventional Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Kaihao XuDepartment of Interventional Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yiming LiuDepartment of Interventional Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Deyao ZhaoDepartment of Irradiation, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xinwei HanDepartment of Interventional Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Ruitai FanDepartment of Irradiation, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
First Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radioisotopes have long been leveraged for internal radiotherapy-mediated cancer treatment. However, such therapeutic approaches are associated with serious side effects, and their efficacy is limited by intratumoral hypoxia. Herein, we prepared a folic acid-decorated palladium decahedral platform capable of enhancing the radiotherapeutic efficacy of iodine-125 (

Indexed as

125 Iesophageal cancerhypoxiananoenzymeradiotherapy

Identifiers

PMID34692667
PMCPMC8531641
OpenAlexW3207062937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.