Evidence map›Paper›PMID 34692640›Full record

ArticleFrontiers in chemistry2021

Synthesis, Computational Pharmacokinetics Report, Conceptual DFT-Based Calculations and Anti-Acetylcholinesterase Activity of Hydroxyapatite Nanoparticles Derived From

Sushma Pradeep, Anisha S Jain, Chandan Dharmashekara, Shashanka K Prasad, Nagaraju Akshatha, R Pruthvish, Raghavendra G Amachawadi, Chandrashekar Srinivasa, Asad Syed, Abdallah M Elgorban and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Molecules (Basel, Switzerland) · 2023
    Article
  9. Review
  10. Cell cycle arrest and apoptotic studies ofFrontiers in oncology · 2023
    Article
  11. Article
  12. Nanoconjugate Synthesis ofMolecules (Basel, Switzerland) · 2022
    Article
  13. Anticholinesterase activity ofFrontiers in pharmacology · 2022
    Article
  14. Article
  15. Synthesis of New 3-Arylcoumarins BearingFrontiers in chemistry · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 5 countries.

Sushma PradeepDepartment of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru, India.
Anisha S JainDepartment of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru, India.
Chandan DharmashekaraDepartment of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru, India.
Shashanka K PrasadDepartment of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru, India.
Nagaraju AkshathaDepartment of Physics, Marimallapa PU College, Mysuru, India.
R PruthvishDepartment of Biotechnology, Acharya Institute of Technology, Bengaluru, India.
Raghavendra G AmachawadiDepartment of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, KS, United States.
Chandrashekar SrinivasaDepartment of Studies in Biotechnology, Davangere University, Shivagangothri, Davangere, India.
Asad SyedDepartment of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Abdallah M ElgorbanDepartment of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Abdulaziz A Al KheraifDental Health Department, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Joaquín Ortega-CastroDepartament de Química, Universitat de les Illes Balears, Palma de Mallorca, Spain.
Juan FrauDepartament de Química, Universitat de les Illes Balears, Palma de Mallorca, Spain.
Norma Flores-HolguínLaboratorio Virtual NANOCOSMOS, Departamento de Medio Ambiente y Energía, Centro de Investigación en Materiales Avanzados, Chihuahua, México.
Chandan ShivamalluDepartment of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru, India.
Shiva Prasad KollurDepartment of Sciences, Amrita School of Arts and Sciences, Amrita Vishwa Vidyapeetham, Mysuru Campus, Mysuru, India.
Daniel Glossman-MitnikLaboratorio Virtual NANOCOSMOS, Departamento de Medio Ambiente y Energía, Centro de Investigación en Materiales Avanzados, Chihuahua, México.
JSS Academy of Higher Education and Research · INKing Saud University · SACentro de Investigación en Materiales Avanzados · MXUniversitat de les Illes Balears · ESAmrita Vishwa Vidyapeetham · INDavangere University · INKansas State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the years, Alzheimer's disease (AD) treatments have been a major focus, culminating in the identification of promising therapeutic targets. A herbal therapy approach has been required by the demand of AD stage-dependent optimal settings. Present study describes the evaluation of anti-acetylcholinesterase (AChE) activity of hydroxyapatite nanoparticles derived from an

Indexed as

Alzheimer’s diseaseamyloid plaquescomputational pharmacokineticsConceptual DFTmolecular dockingneurofibrillary tanglesneuropathology

Identifiers

PMID34692640
PMCPMC8529163
OpenAlexW3206056108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.