Evidence map›Paper›PMID 34692560›Full record

ArticleFrontiers in cellular and infection microbiology2021

Analysis of Risk Factors for Carbapenem-Resistant Klebsiella pneumoniae Infection and Its Effect on the Outcome of Early Infection After Kidney Transplantation.

Fei Zhang, Jinbiao Zhong, Handong Ding, Jiashan Pan, Jing Yang, Tianchi Lan, Yiding Chen, Guiyi Liao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Exploring current hypervirulentFrontiers in microbiology · 2025
    Review
  7. Article
  8. Article
  9. Observational
  10. Burden and Management of Multi-Drug Resistant Organism Infections in Solid Organ Transplant Recipients Across the World: A Narrative Review.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Review
  11. Article
  12. Article
  13. Carbapenem-ResistantClinical interventions in aging · 2023
    Article
  14. Analysis of Risk Factors for Carbapenem ResistantInfection and drug resistance · 2023
    Article
  15. Article
  16. Review
  17. Article
  18. Epidemic, risk factors of carbapenem-resistantFrontiers in cellular and infection microbiology · 2022
    Article
  19. Effect of Carbapenem-ResistantInfection and drug resistance · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Fei ZhangDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, HeFei, China.
Jinbiao ZhongDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, HeFei, China.
Handong DingDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, HeFei, China.
Jiashan PanDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, HeFei, China.
Jing YangDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, HeFei, China.
Tianchi LanDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, HeFei, China.
Yiding ChenDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, HeFei, China.
Guiyi LiaoDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, HeFei, China.
Anhui Medical University · CNFirst Affiliated Hospital of Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Infections remain a major cause of morbidity and mortality in kidney transplant (KT) recipients. This study was performed to identify the overall prevalence of early infections, prevalence of carbapenem-resistant Klebsiella pneumoniae (CRKP) infection after KT, one-year postoperative mortality in patients with early infections and risk factors for CRKP infections. Methods: We conducted a retrospective study of all patients who received KT in our hospital between January 2017 and December 2019. We evaluated the demographic, clinical, infection characteristics and the one-year postoperative outcomes. Results: Among the 419 patients who received KT between January 2017 and December 2019, 150 patients had at least one infection within 90 days after KT. The total prevalence of early infections was 36.1% (150/415), the prevalence of early CRKP infections was 10.4% (43/415), and the one-year postoperative mortality was 15.3% (23/150) in patients with early infections. The risk factors independently related to one-year postoperative mortality were mechanical ventilation (MV) > 48 h (Odds ratio (OR)= 13.879, 95%Confidence interval (CI): 2.265~85.035; P=0.004) and CRKP infection (OR=6.751, 95% CI: 1.051~43.369; P =0.044). MV> 48 h was independently related to CRKP infection (OR=3.719, 95% CI: 1.024~13.504; P=0.046). Kaplan-Meier survival curves showed that the one-year survival rate of patients infected with CRKP in the early postoperative stage was significantly lower than that of uninfected patients. Conclusions: In general, the prevalence of early infections after KT is high, and CRKP infection is closely correlated with poor prognosis. The effective prevention and treatment of CRKP infection is an important way to improve the one-year survival rate after KT.

Indexed as

Kidney TransplantationKlebsiella InfectionsAnti-Bacterial AgentsCarbapenemsDrug Resistance, BacterialHumansKlebsiella pneumoniaeRetrospective StudiesRisk FactorsAnti-Bacterial AgentsCarbapenemscarbapenem-resistant Klebsiella pneumoniaeearly infectionskidney transplantmultidrug resistancerisk factors

Identifiers

PMID34692560
PMCPMC8535439
OpenAlexW3205005502

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.