Evidence map›Paper›PMID 34692432›Full record

ArticleAfrican journal of disability2021

Impact of prostheses on quality of life and functional status of transfemoral amputees in Tanzania.

Ericka P von Kaeppler, Alexander Hetherington, Claire A Donnelley, Syed H Ali, Corin Shirley, Sravya T Challa, Emily Lutyens, Billy T Haonga, Saam Morshed, Jan Andrysek and 1 more

Open access · goldAbstract read
In one paragraph

Article in African journal of disability, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Frugal Innovations in Orthopaedics.Current reviews in musculoskeletal medicine · 2025
    Review
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  6. Article
  7. Article
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  12. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Ericka P von KaepplerInstitute of Global Orthopaedics and Traumatology, University of California San Francisco, San Francisco, United States of America.ORCID https://orcid.org/0000-0002-9495-3755
Alexander HetheringtonInstitute of Global Orthopaedics and Traumatology, University of California San Francisco, San Francisco, United States of America.ORCID https://orcid.org/0000-0002-7818-0166
Claire A DonnelleyInstitute of Global Orthopaedics and Traumatology, University of California San Francisco, San Francisco, United States of America.ORCID https://orcid.org/0000-0001-7316-6368
Syed H AliInstitute of Global Orthopaedics and Traumatology, University of California San Francisco, San Francisco, United States of America.ORCID https://orcid.org/0000-0003-0524-5376
Corin ShirleyInstitute of Global Orthopaedics and Traumatology, University of California San Francisco, San Francisco, United States of America.ORCID https://orcid.org/0000-0003-4090-0356
Sravya T ChallaInstitute of Global Orthopaedics and Traumatology, University of California San Francisco, San Francisco, United States of America.ORCID https://orcid.org/0000-0003-0045-1015
Emily LutyensLegWorks, Inc., Buffalo, United States of America.ORCID https://orcid.org/0000-0002-3154-4743
Billy T HaongaDepartment of Orthopaedic Surgery, Muhimbili Orthopaedic Institute, Dar es Salaam, Tanzania.ORCID https://orcid.org/0000-0001-9342-298X
Saam MorshedInstitute of Global Orthopaedics and Traumatology, University of California San Francisco, San Francisco, United States of America.ORCID https://orcid.org/0000-0002-8847-8919
Jan AndrysekLegWorks, Inc., Buffalo, United States of America.ORCID https://orcid.org/0000-0002-4976-1228
David W ShearerInstitute of Global Orthopaedics and Traumatology, University of California San Francisco, San Francisco, United States of America.ORCID https://orcid.org/0000-0002-1356-6391
University of California, San Francisco · USHolland Bloorview Kids Rehabilitation Hospital · CAMuhimbili Orthopaedic Institute · TZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe rise of diabetes and traumatic injury has increased limb loss-related morbidity in low- and middle-income countries (LMICs). Despite this, the majority of amputees in LMICs have no access to prosthetic devices, and the magnitude of prosthesis impact on quality of life (QOL ) and function has not been quantified.

objectivesQuantify the impact of prostheses on QOL and function in Tanzanian transfemoral amputees.

methodA prospective cohort study was conducted. Transfemoral amputees at Muhimbili Orthopaedic Institute were assessed twice before and three times after prosthetic fitting using EuroQol-5D-3L (EQ-5D-3L), Prosthetic Limb Users Survey of Mobility (PLUS-M), 2-minute walk test (2MWT) and Physiologic Cost Index (PCI). Data were analysed for change over time. Subgroup analysis was performed for amputation aetiology (vascular or non-vascular) and prosthesis use.

resultsAmongst 30 patients, EQ-5D, PLUS-M and 2MWT improved after prosthesis provision (

conclusionProsthesis provision to transfemoral amputees in an LMIC improved QOL and function. This benefit was greater for non-vascular amputation aetiologies. Quality of life and function returned to pre-prosthesis levels with discontinued use of prosthesis.

Indexed as

above-knee prosthesisfunctional statuslow- and middle-income countriesquality of lifeTanzaniatransfemoral amputation

Identifiers

PMID34692432
PMCPMC8517763
OpenAlexW3189558046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.