Evidence map›Paper›PMID 34692386›Full record

ArticleGlobal heart2021

Persistent Hypertension Up to One Year Postpartum among Women with Hypertensive Disorders in Pregnancy in a Low-Resource Setting: A Prospective Cohort Study.

Salisu M Ishaku, Tukur Jamilu, Agbo P Innocent, Kayode A Gbenga, Dattijo Lamaran, Oyeneyin Lawal, Charlotte E Warren, Owa O Olorunfemi, Hanifah D Abubakar, Tunau Karima and 7 more

Open access · goldAbstract read
In one paragraph

Article in Global heart, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Biomarkers of endothelial glycocalyx dysfunction in pregnancy: a systematic review of clinical relevance and detection techniques.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Pooled it
  2. Pooled it
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  4. Geographic Age Cohort Study of Maternal Hypertensive Disorders.Journal of the American Heart Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 12 institutions in 4 countries.

Salisu M IshakuPopulation Council Nigeria, NG.
Tukur JamiluBayero University/Aminu Kano Teaching Hospital Kano, Kano State, NG.
Agbo P InnocentPopulation Council Nigeria, NG.
Kayode A GbengaInstitute of Human Virology, Abuja, NG.
Dattijo LamaranAbubakar Tafawa Balewa University Teaching Hospital, Bauchi, Bauchi State, NG.
Oyeneyin LawalUniversity of Medical Sciences Teaching Hospital, Ondo, Ondo State, NG.
Charlotte E WarrenPopulation Council-Washington, DC, US.
Owa O OlorunfemiMother and Child Hospital, Akure, NG.
Hanifah D AbubakarMuhammad Abdullahi Wase Teaching Hospital, Kano, Kano State, NG.
Tunau KarimaUsman DanFodio University Teaching hospital, Sokoto, Sokoto State, NG.
Odusolu O PatienceUniversity of Calabar Teaching Hospital, Calabar, Cross River State, NG.
Abdulkarim MusaFederal Medical Center, Lokoja, Kogi State, NG.
Onyebuchi K AzubuikeFederal Teaching Hospital, Abakaliki, Ebonyi State, NG.
Aminu M BaffahAbubakar Tafawa Balewa University Teaching Hospital, Bauchi, Bauchi State, NG.
Arie FranxErasmus Medical Center, University Medical Center Rotterdam, NL.
Diederick E GrobbeeJulius Global Health, Julius Center for Health Science and Primary Care, UMC Utrecht, Utrecht University, NL.
Joyce L BrowneJulius Global Health, Julius Center for Health Science and Primary Care, UMC Utrecht, Utrecht University, NL.
Utrecht University · NLAbubakar Tafawa Balewa University · NGAminu Kano Teaching Hospital · NGErasmus MC · NLFederal Teaching Hospital Abakaliki · NGMedical Laboratory Science Council of Nigeria · NGMother Hospital · INOndo State University of Science and Technology · NGPopulation Council · USUniversity Medical Center Utrecht · NLUniversity of Calabar · NGUsmanu Danfodiyo University Teaching Hospital, Sokoto · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hypertensive disorders in pregnancy (HDPs) are associated with lifelong cardiovascular disease risk. Persistent postpartum hypertension in HDPs could suggest progression to chronic hypertension. This phenomenon has not been well examined in low- and middle-income countries (LIMCs), and most previous follow-ups typically last for maximally six weeks postpartum. We assessed the prevalence of persistent hypertension up to one year in women with HDPs in a low resource setting and determined associated risk factors. Methodology: A prospective cohort study of women conducted at eight tertiary health care facilities in seven states of Nigeria. Four hundred and ten women with any HDP were enrolled within 24 hours of delivery and followed up at intervals until one year postpartum. Descriptive statistics were performed to express the participants' characteristics. Univariable and multivariable logistic regressions were conducted to identify associated risk factors. Results: Of the 410 women enrolled, 278 were followed up to one year after delivery (follow-up rate 68%). Among women diagnosed with gestational hypertension and pre-eclampsia/eclampsia, 22.3% (95% CI; 8.3-36.3) and 62.1% (95% CI; 52.5-71.9), respectively, had persistent hypertension at six months and this remained similar at one year 22.3% (95% CI; 5.6-54.4) and 61.2% (95% CI; 40.6-77.8). Maternal age and body mass index were significant risk factors for persistent hypertension at one year [aORs = 1.07/year (95% CI; 1.02-1.13) and 1.06/kg/m Conclusion: This study showed a substantial prevalence of persistent hypertension beyond puerperium. Health systems in LMICs need to be organized to anticipate and maintain postpartum monitoring until blood pressure is normalized, or women referred or discharged to family physicians as appropriate. In particular, attention should be given to women who are obese, and or of higher maternal age.

Indexed as

Hypertension, Pregnancy-InducedPre-EclampsiaBlood PressureFemaleHumansPostpartum PeriodPregnancyProspective StudiesRisk FactorsHypertensive Disorder in PregnancyNigeriaPersistent Hypertension

Identifiers

PMID34692386
PMCPMC8428291
OpenAlexW3197970502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.