Evidence map›Paper›PMID 34692375›Full record

ArticleAnalytical cellular pathology (Amsterdam)2021

Assessment of Immune Cell Populations in Tumor Tissue and Peripheral Blood Samples from Head and Neck Squamous Cell Carcinoma Patients.

Ana Caruntu, Liliana Moraru, Mihaela Surcel, Adriana Munteanu, Cristiana Tanase, Carolina Constantin, Sabina Zurac, Constantin Caruntu, Monica Neagu

Open access · goldAbstract read
In one paragraph

Article in Analytical cellular pathology (Amsterdam), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Ana CaruntuDepartment of Oral and Maxillofacial Surgery, "Carol Davila" Central Military Emergency Hospital, 010825 Bucharest, Romania.
Liliana MoraruDepartment of Oral and Maxillofacial Surgery, "Carol Davila" Central Military Emergency Hospital, 010825 Bucharest, Romania.
Mihaela SurcelImmunology Department, Victor Babes National Institute of Pathology, 050096 Bucharest, Romania.
Adriana MunteanuImmunology Department, Victor Babes National Institute of Pathology, 050096 Bucharest, Romania.
Cristiana TanaseBiochemistry Laboratory, Victor Babes National Institute of Pathology, 050096 Bucharest, Romania.
Carolina ConstantinImmunology Department, Victor Babes National Institute of Pathology, 050096 Bucharest, Romania.
Sabina ZuracDepartment of Pathology, Colentina University Hospital, Bucharest 020125, Romania.ORCID https://orcid.org/0000-0002-3498-8454
Constantin CaruntuDepartment of Physiology, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID https://orcid.org/0000-0003-4530-7965
Monica NeaguImmunology Department, Victor Babes National Institute of Pathology, 050096 Bucharest, Romania.
Titu Maiorescu University · ROCarol Davila University of Medicine and Pharmacy · ROInstitutul National Victor Babes · ROUniversity of Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Head and neck squamous cell carcinoma (HNSCC) is a common type of cancer worldwide. Strong connections have been revealed between immune cells and the pathogenesis of HNSCC. Important differences regarding the levels of immune cell subpopulations in both peripheral circulation and tumor microenvironment were emphasized, with some of them having prognostic significance. In our study, we performed an analysis of immune changes in the tumor tissue and the peripheral blood of untreated HNSCC patients, investigating the proportions of different immune cell populations in these two compartments. The local infiltrating lymphocytes were mainly cytotoxic T cells (CD8

Indexed as

AgedAged, 80 and overFemaleHead and Neck NeoplasmsHumansLymphocytes, Tumor-InfiltratingMaleMiddle AgedSquamous Cell Carcinoma of Head and NeckTumor Microenvironment

Identifiers

PMID34692375
PMCPMC8536455
OpenAlexW3206766277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.