Evidence map›Paper›PMID 34692287›Full record

ArticleCureus2021

A Case of Mal De Meleda: The Rare Presentation of Palmoplantar Keratoderma Disease.

Vamsi Kalyan, Tarun K Suvvari, Venkata Dinesh Kumar Kandula, Aparajeya Shanker, Lolita Matiashova

Abstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Pain Hypersensitivity in SLURP1 and SLURP2 Knock-out Mouse Models of Hereditary Palmoplantar Keratoderma.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vamsi KalyanMedicine and Surgery, Rangaraya Medical College, Kakinada, IND.
Tarun K SuvvariMedicine and Surgery, Dr. N.T.R University of Health Sciences, Vijayawada, IND.
Venkata Dinesh Kumar KandulaMedicine, GSL Medical College, Rajahmundry, IND.
Aparajeya ShankerFaculty of Medicine, Medical University of Pleven, Pleven, BGR.
Lolita MatiashovaDepartment of Comprehensive Risk Reduction for Chronic Non-Communicable Diseases, L.T. Malaya Therapy National Institute of the National Academy of Medical Sciences of Ukraine, Kharkiv, UKR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mal de Meleda (MDM) is a rare sub-type of palmoplantar keratoderma (PPK) disease. The primary symptoms of PPK are scleroatrophy, transient keratoderma, scleroatrophic erythema, pseudoainhum around the digits, and perioral erythema. MDM is a pathology with a difficult clinical course. This case study presents two cases of MDM in siblings born out of second-degree consanguinity. The presenting complaint was the peeling of the palmar skin since birth. Both patients were treated with acitretin orally (dose: 10 mg) for three months and tretinoin (topical) for two months. The prognosis was good after three months of treatment.

Indexed as

clinical dermatologymal de meledapalmoplantar keratodermarare diseasesscleroatrophic erythema

Identifiers

PMID34692287
PMCPMC8523366

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.