Evidence map›Paper›PMID 34692220›Full record

ArticleBiomedical optics express2021

Robust functional imaging of taste sensation with a Bessel beam.

Jisoo Han, Seonghoon Kim, Pyonggang Choi, Sungho Lee, Yongjae Jo, Eunsoo Kim, Myunghwan Choi

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Correlative Imaging Platform Linking Taste Cell Function to Molecular Identity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jisoo HanDepartment of Biomedical Engineering, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Seonghoon KimSchool of Biological Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Pyonggang ChoiSchool of Biological Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Sungho LeeSchool of Biological Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Yongjae JoDepartment of Biomedical Engineering, Sungkyunkwan University, Suwon 16419, Republic of Korea.ORCID https://orcid.org/0000-0001-6585-0012
Eunsoo KimSchool of Biological Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Myunghwan ChoiSchool of Biological Sciences, Seoul National University, Seoul 08826, Republic of Korea.ORCID https://orcid.org/0000-0002-4235-7003
Seoul National University · KRSungkyunkwan University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional imaging of intact taste cells in response to various tastant solutions poses a technical challenge since the refractive index of the immersion medium dynamically changes during tastant delivery. Critically, the focal shift introduced by high-index tastant solutions has been the fundamental limit in experimental design. Here we seek to address this issue by introducing an axially elongated Bessel beam in two-photon microscopy. Compared to the conventional Gaussian beam, the Bessel beam provides superior robustness to the index-induced focal shift, allowing us to acquire near artifact-free imaging of taste cells in response to a physiological taste stimulus.

Identifiers

PMID34692220
PMCPMC8515959
OpenAlexW3193885445

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.