Evidence map›Paper›PMID 34692214›Full record

ArticleBiomedical optics express2021

Ultrawide field, distortion-corrected ocular shape estimation with MHz optical coherence tomography (OCT).

Bingyao Tan, Ryan P McNabb, Feihui Zheng, Yin Ci Sim, Xinwen Yao, Jacqueline Chua, Marcus Ang, Quan V Hoang, Anthony N Kuo, Leopold Schmetterer

Abstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Evaluation of retinochoroidal changes after implantable collamer lens implantation: insights from UWF-SS-OCTA and AI-based 3D modeling.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Widefield OCT angiography.Progress in retinal and eye research · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Article
  15. Article
  16. Advances in OCT Imaging in Myopia and Pathologic Myopia.Diagnostics (Basel, Switzerland) · 2022
    Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bingyao TanSERI-NTU Advanced Ocular Engineering (STANCE), Singapore, Singapore.ORCID https://orcid.org/0000-0002-6532-9603
Ryan P McNabbDuke University Medical Center, Durham, NC 27607, USA.ORCID https://orcid.org/0000-0002-1686-4191
Feihui ZhengSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
Yin Ci SimSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.ORCID https://orcid.org/0000-0002-9643-9266
Xinwen YaoSERI-NTU Advanced Ocular Engineering (STANCE), Singapore, Singapore.ORCID https://orcid.org/0000-0001-8813-4676
Jacqueline ChuaSERI-NTU Advanced Ocular Engineering (STANCE), Singapore, Singapore.
Marcus AngSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
Quan V HoangSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
Anthony N KuoSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
Leopold SchmettererSERI-NTU Advanced Ocular Engineering (STANCE), Singapore, Singapore.

Funding

Whole Eye Optical Coherence Tomography to Improve Refractive Surgery and Eye CareR01EY024312 · NEI · DUKE UNIVERSITY · PI KUO, ANTHONY NANLIN · 2015 to 2024
$3.5M
NEI NIH HHS R01 EY024312
6 · The paper itself

Abstract

Ocular deformation may be associated with biomechanical alterations in the structures of the eye, especially the cornea and sclera in conditions such as keratoconus, congenital glaucoma, and pathological myopia. Here, we propose a method to estimate ocular shape using an ultra-wide field MHz swept-source optical coherence tomography (SS-OCT) with a Fourier Domain Mode-Locked (FDML) laser and distortion correction of the images. The ocular biometrics for distortion correction was collected by an IOLMaster 700, and localized Gaussian curvature was proposed to quantify the ocular curvature covering a field-of-view up to 65°×62°. We achieved repeatable curvature shape measurements (intraclass coefficient = 0.88 ± 0.06) and demonstrated its applicability in a pilot study with individuals (N = 11) with various degrees of myopia.

Identifiers

PMID34692214
PMCPMC8515957

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.