ArticleNational science review2020
Rapid phenotypic evolution with shallow genomic differentiation during early stages of high elevation adaptation in Eurasian Tree Sparrows.
Article in National science review, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 65 citations in OpenAlex.
- Chromosome-level genome assembly of Trichiurus japonicus resolves species boundaries and evolutionary history of cutlassfishes in Northwest Pacific.BMC genomics · 2026Article
- Diverse mitogenomic variations contribute to population differentiation in Eurasian tree sparrows (Zoological research · 2026Article
- Article
- Divergent Cardiovascular Adaptations and Gene Regulation in High-Elevation Natives and Recent Colonizers of the Qinghai-Tibetan Plateau.Molecular biology and evolution · 2025Article
- Genome-wide scan for selection signatures reveals novel insights into the adaptive capacity characteristics in three Chinese cattle breeds.BMC genomics · 2025Article
- A comparison of seasonal flexibility in pectoralis muscle fiber type and enzyme activity in migratory and resident sparrow species.The Journal of experimental biology · 2025Article
- Article
- Review
- Gene expression plasticity followed by genetic change during colonization in a high-elevation environment.eLife · 2024Article
- Genomic Variation, Population History, and Long-Term Genetic Adaptation to High Altitudes in Tibetan Partridge (Perdix hodgsoniae).Molecular biology and evolution · 2023Article
- Developmental environment contributes to rapid trait shifts among newly colonized subterranean habitats.Zoological research · 2023Article
- Enlarged fins of Tibetan catfish provide new evidence of adaptation to high plateau.Science China. Life sciences · 2023Article
- Genetic diversity and gene expression diversity shape the adaptive pattern of the aquatic plant Batrachium bungei along an altitudinal gradient on the Qinghai-Tibet plateau.Plant molecular biology · 2023Article
- Variation in gene expression along an elevation gradient ofFrontiers in plant science · 2023Article
- The metabolic adaptation in wild vertebrates via omics approaches.Life metabolism · 2022Review
- Comparative genomics reveals putative evidence for high-elevation adaptation in the American pika (Ochotona princeps).G3 (Bethesda, Md.) · 2022Review
- Comparative transcriptomic and metabolomic analysis reveals pectoralis highland adaptation across altitudinal songbirds.Integrative zoology · 2022Article
- The combination of genomic offset and niche modelling provides insights into climate change-driven vulnerability.Nature communications · 2022Article
- Comparison between short-term stress and long-term adaptive responses reveal common paths to molecular adaptation.iScience · 2022Article
- Article
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Authors and funding
22 authors at 10 institutions in 4 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Known as the 'third polar region', the Qinghai-Tibet Plateau represents one of the harshest highland environments in the world and yet a number of organisms thrive there. Previous studies of birds, animals and humans have focused on well-differentiated populations in later stages of phenotypic divergence. The adaptive processes during the initial phase of highland adaptation remain poorly understood. We studied a human commensal, the Eurasian Tree Sparrow, which has followed human agriculture to the Qinghai-Tibet Plateau. Despite strong phenotypic differentiation at multiple levels, in particular in muscle-related phenotypes, highland and lowland populations show shallow genomic divergence and the colonization event occurred within the past few thousand years. In a one-month acclimation experiment investigating phenotypic plasticity, we exposed adult lowland tree sparrows to a hypoxic environment and did not observe muscle changes. Through population genetic analyses, we identified a signature of polygenic adaptation, whereby shifts in allele frequencies are spread across multiple loci, many of which are associated with muscle-related processes. Our results reveal a case of positive selection in which polygenic adaptation appears to drive rapid phenotypic evolution, shedding light on early stages of adaptive evolution to a novel environment.
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