Durable superamphiphobic silica aerogel surfaces for the culture of 3D cellular spheroids.

Lianyi Xu, Shuangshuang Chen, Xuemin Lu, Qinghua Lu

Abstract read

In one paragraph

Article in National science review, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Mammalian Cell Spheroids on Mixed Organic-Inorganic Superhydrophobic Coating.Molecules (Basel, Switzerland) · 2022
Article

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lianyi XuSchool of Materials Science, Institute of Energy Equipment Materials, Shanghai Dianji University, Shanghai 201306, China.

Shuangshuang ChenSchool of Chemical Science and Engineering, Tongji University, Shanghai 200092, China.

Xuemin LuSchool of Chemistry and Chemical Engineering, State Key Laboratory of Metal Matrix Composite, Shanghai Jiao Tong University, Shanghai 200240, China.

Qinghua LuSchool of Chemical Science and Engineering, Tongji University, Shanghai 200092, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 3D multicellular spheroids with intact cell-cell junctions have major roles in biological research by virtue of their unique advantage of mimicking the cellular physiological environments. In this work, a durable superamphiphobic silica aerogel surface (SSAS) has been fabricated for the upward culture of 3D multicellular spheroids. Poly(3,4-ethylenedioxythiophene) (PEDOT) was first electrodeposited on a conductive steel mesh as a first template for porous silica coating. Soot particles were then applied as a second template to construct a cauliflower-like silica aerogel nanostructure. After fluorination, a hierarchical structure with re-entrant curvature was finally fabricated as a durable superamphiphobic surface. This superamphiphobic surface also presented excellent antifouling towards biomacromolecules and cells, which has been demonstrated by the successful upward culture of cell spheroids. The upward culture makes the observation of cellular behavior

Indexed as

cell spheroidsdurabilityelectrochemistrysilica aerogelsuperamphiphobicity

Identifiers

PMID34692003

DOI10.1093/nsr/nwz095

PMCPMC8291414

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.