ArticleNational science review2021
Genomic mosaicism due to homoeologous exchange generates extensive phenotypic diversity in nascent allopolyploids.
Article in National science review, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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36 citing papers in PubMed, 63 citations in OpenAlex.
- Homoeologous exchange-associated ABA catabolism rewiring contributes to salinity tolerance in a synthetic tetraploid rice.Plant cell reports · 2026Article
- HSP101-encoding NEO-TETRAPLOID RICE FERTILITY GENE 1 regulates tapetum development through interaction with SAPK2 in polyploid rice.Journal of integrative plant biology · 2026Article
- Causes and consequences of cytonuclear incompatibility in hybrids of flowering plants.Journal of experimental botany · 2026Review
- Hybridization and Polyploidy Shaped the Evolutionary History of a Complex of Cryptic Species in European Woodrushes (Luzula sect. Luzula).Systematic biology · 2026Article
- Article
- The polyploid continuum and the landscape of polyploid genomic variation.American journal of botany · 2025Review
- Genome analyses and breeding of polyploid crops.Nature plants · 2025Review
- Diploidization in a wild rice allopolyploid is both episodic and gradual.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Rapid formation of stable autotetraploid rice from genome-doubled F1 hybrids of japonica-indica subspecies.Nature plants · 2025Article
- Geo-climatic factors co-drive the phenotypic diversity of wild hemp (Cannabis sativa L.) in the Potohar Plateau and Lesser Himalayas.BMC plant biology · 2024Article
- Contribution of homoeologous exchange to domestication of polyploid Brassica.Genome biology · 2024Article
- Complex Polyploids: Origins, Genomic Composition, and Role of Introgressed Alleles.Systematic biology · 2024Article
- Cytological Observation and RNA-Seq Analyses RevealPlants (Basel, Switzerland) · 2024Article
- Evolutionary divergence of subgenomes in common carp provides insights into speciation and allopolyploid success.Fundamental research · 2024Article
- The genome and population genomics of allopolyploid Coffea arabica reveal the diversification history of modern coffee cultivars.Nature genetics · 2024Article
- Polyploid plants take cytonuclear perturbations in stride.The Plant cell · 2024Article
- Hagfish genome elucidates vertebrate whole-genome duplication events and their evolutionary consequences.Nature ecology & evolution · 2024Article
- Downregulation of the expression of subgenomic chromosome A7 genes promotes plant height in resynthesized allopolyploid Brassica napus.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Karyotyping of aneuploid and polyploid plants from low coverage whole-genome resequencing.BMC plant biology · 2023Article
- Main Habitat Factors Driving the Phenotypic Diversity ofPlants (Basel, Switzerland) · 2023Article
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Authors and funding
17 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Allopolyploidy is an important process in plant speciation, yet newly formed allopolyploid species typically suffer from extreme genetic bottlenecks. One escape from this impasse might be homoeologous meiotic pairing, during which homoeologous exchanges (HEs) generate phenotypically variable progeny. However, the immediate genome-wide patterns and resulting phenotypic diversity generated by HEs remain largely unknown. Here, we analyzed the genome composition of 202 phenotyped euploid segmental allopolyploid individuals from the fourth selfed generation following chromosomal doubling of reciprocal F1 hybrids of crosses between rice subspecies, using whole-genome sequencing. We describe rampant occurrence of HEs that, by overcoming incompatibility or conferring superiority of hetero-cytonuclear interactions, generate extensive and individualized genomic mosaicism across the analyzed tetraploids. We show that the resulting homoeolog copy number alteration in tetraploids affects known-function genes and their complex genetic interactions, in the process creating extraordinary phenotypic diversity at the population level following a single initial hybridization. Our results illuminate the immediate genomic landscapes possible in a tetraploid genomic environment, and underscore HE as an important mechanism that fuels rapid phenotypic diversification accompanying the initial stages of allopolyploid evolution.
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