Evidence map›Paper›PMID 34691420›Full record

ArticleAnnals of medicine and surgery (2012)2021

Exercise adaptations and TGF-β1 levels in recreational cyclists.

Ida Ayu Eka Widiastuti, Aryadi Arsyad, Irfan Idris, Ilhamjaya Patellongi, Hamsu Kadriyan, Gede Wira Buanayuda, Dian Puspita Sari, Rohadi Muhammad Rosyidi

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Article in Annals of medicine and surgery (2012), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ida Ayu Eka WidiastutiDepartment of Physiology, Medical Faculty of Mataram University, Mataram, Indonesia.
Aryadi ArsyadPostgraduate Program, Medical Faculty of Hasanuddin University, Makassar, Indonesia.
Irfan IdrisPostgraduate Program, Medical Faculty of Hasanuddin University, Makassar, Indonesia.
Ilhamjaya PatellongiPostgraduate Program, Medical Faculty of Hasanuddin University, Makassar, Indonesia.
Hamsu KadriyanDepartment of Otolaryngology Head and Neck Surgery, Medical Faculty of Mataram University, Mataram, Indonesia.
Gede Wira BuanayudaDepartment of Biomedical Sciences, Medical Faculty of Mataram University, Mataram, Indonesia.
Dian Puspita SariDepartment of Medical Education, Medical Faculty of Mataram University, Mataram, Indonesia.
Rohadi Muhammad RosyidiDepartment of Neurosurgery Medical Faculty of Mataram University, West Nusa Tenggara General Hospital, Mataram, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCycling is a physical exercise that is widely performed to improve physical fitness. Regular physical exercise will lead to adaptations to exercise. This adaptation is useful in suppressing the production of reactive oxygen stress (ROS) generated in response to cellular metabolism that uses oxygen. Transforming growth factor beta-1 (TGF-β1) plays a role in increasing the production of ROS, thus, when the concentration is low, it would lead to an improvement in physical fitness. This study aims to compare levels of TGF-β1 between recreational cyclists and sedentary groups. In addition, this research also compares several other parameters, which are fasting blood sugar levels and lipid profiles (triglycerides, total cholesterol, HDL cholesterol, and LDL cholesterol) between cyclists and sedentaries.

methodsThis was an observational analytical study with a cross-sectional design. The research subjects consisted of 2 groups, each consisting of 21 participants, namely the recreational cyclist and the sedentary group. Anthropometric examinations were carried out, including body weight, height, body mass index, waist circumference, and body fat percentage. Fasting blood glucose concentration and lipid profile (Triglyceride -

resultsThe anthropometric variables, other than body height, did not differ significantly between the two groups, so did the fasting blood glucose concentration. Nevertheless, the lipid profile (TG, Total C, HDL-C and LDL-C) were found to be significantly better in the cyclist group (p < 0.05).The mean level of TGF-β1 in recreational cyclists was 8, 908.48 pg/ml, lower than the control group, 10, 229.28 pg/ml. The results of the unpaired

conclusionThe levels of TGF-β1 in the recreational cyclist group were lower than the sedentary group. Regular physical exercise will trigger exercise adaptations that can suppress latent TGF-β1 activation.

Indexed as

AdaptationCyclistsRegular physical exerciseTransforming growth factor beta 1

Identifiers

PMID34691420
PMCPMC8519766

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