Evidence map›Paper›PMID 34691389›Full record

ArticleClinical and translational allergy2021

Prospective Italian real-world study of mepolizumab in severe eosinophilic asthma validates retrospective outcome reports.

Laura Pini, Cristiano Caruso, Stefania Colantuono, Diego Bagnasco, Aoife Maxwell, Robert G Price, Peter Howarth, Giorgio Walter Canonica, Italian investigators of REALITI‐A

Abstract read
In one paragraph

Article in Clinical and translational allergy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Improving patient outcomes: Mepolizumab's impact in IL-5-mediated diseases.Lung India : official organ of Indian Chest Society · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Specific Therapy for T2 Asthma.Journal of personalized medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laura PiniRespiratory Unit Spedali Civili di Brescia Brescia Italy.
Cristiano CarusoDepartment of Medical and Surgical Sciences Fondazione Policlinico A. Gemelli IRCCS Rome Italy.
Stefania ColantuonoDepartment of Medical and Surgical Sciences Fondazione Policlinico A. Gemelli IRCCS Rome Italy.
Diego BagnascoAllergy and Respiratory Diseases IRCCS Policlinico San Martino University of Genoa Genoa Italy.
Aoife MaxwellReal World Study Delivery Value Evidence and Outcomes Global Medical GSK Stevenage Hertfordshire UK.
Robert G PriceBiostatistics R&D GSK Stevenage Hertfordshire UK.
Peter HowarthGlobal Medical Global Specialty & Primary Care TA GSK House Brentford Middlesex UK.ORCID https://orcid.org/0000-0003-0619-7927
Giorgio Walter CanonicaDepartment of Biomedical Sciences Humanitas University Milan Italy.
Italian investigators of REALITI‐A

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID34691389
PMCPMC8517195

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.