Evidence map›Paper›PMID 34691351›Full record

ArticleThe annals of applied statistics2019

MICROSIMULATION MODEL CALIBRATION USING INCREMENTAL MIXTURE APPROXIMATE BAYESIAN COMPUTATION.

Carolyn M Rutter, Jonathan Ozik, Maria DeYoreo, Nicholson Collier

Open access · bronzeAbstract read
In one paragraph

Article in The annals of applied statistics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 6 citations in OpenAlex.

  1. Estimating the Opportunity for Early Detection of Ovarian Cancer Using Individual-Patient Data from a Large Randomized Controlled Trial.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Trial
  2. Validation of Colorectal Cancer Models on Long-term Outcomes from a Randomized Controlled Trial.Medical decision making : an international journal of the Society for Medical Decision Making · 2020
    Trial
  3. Article
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  9. A Scoping Review on Calibration Methods for Cancer Simulation Models.Medical decision making : an international journal of the Society for Medical Decision Making · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. A Portfolio Approach to Massively Parallel Bayesian Optimization.The journal of artificial intelligence research · 2025
    Article
  15. Review
  16. Review
  17. DISTRIBUTED MODEL EXPLORATION WITH EMEWS.Proceedings of the ... Winter Simulation Conference. Winter Simulation Conference · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Carolyn M RutterRAND Corporation.
Jonathan OzikUniversity of Chicago.
Maria DeYoreoRAND Corporation.
Nicholson CollierUniversity of Chicago.
Argonne National Laboratory · USRAND Corporation · US

Funding

Comparative Modeling of Effective Policies for Colorectal Cancer ControlU01CA253913 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI RUTTER, CAROLYN M, ZAUBER, ANN GRAHAM · 2020 to 2025
$6.5M
Comparative Modeling of Colorectal Cancer: Informing Health Policies and Prioritizing Future ResearchU01CA199335 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI KUNTZ, KAREN M, LANSDORP-VOGELAAR, IRIS · 2015 to 2019
$5.5M
Beagle-2S10OD018495 · OD · UNIVERSITY OF CHICAGO · PI FOSTER, IAN · 2014 to 2014
$2.0M
Adaptive Simulation to Enable Anatomic-scale Agent-basedR01GM115839 · NIGMS · UNIVERSITY OF CHICAGO · PI AN, GARY, MACAL, CHARLES MARTIN · 2015 to 2017
$1.2M
NCI NIH HHS U01 CA199335NCI NIH HHS U01 CA253913NIGMS NIH HHS R01 GM115839NIH HHS S10 OD018495
6 · The paper itself

Abstract

Microsimulation models (MSMs) are used to inform policy by predicting population-level outcomes under different scenarios. MSMs simulate individual-level event histories that mark the disease process (such as the development of cancer) and the effect of policy actions (such as screening) on these events. MSMs often have many unknown parameters; calibration is the process of searching the parameter space to select parameters that result in accurate MSM prediction of a wide range of targets. We develop Incremental Mixture Approximate Bayesian Computation (IMABC) for MSM calibration, which results in a simulated sample from the posterior distribution of model parameters given calibration targets. IMABC begins with a rejection-based ABC step, drawing a sample of points from the prior distribution of model parameters and accepting points that result in simulated targets that are near observed targets. Next, the sample is iteratively updated by drawing additional points from a mixture of multivariate normal distributions and accepting points that result in accurate predictions. Posterior estimates are obtained by weighting the final set of accepted points to account for the adaptive sampling scheme. We demonstrate IMABC by calibrating CRC-SPIN 2.0, an updated version of a MSM for colorectal cancer (CRC) that has been used to inform national CRC screening guidelines.

Indexed as

Adaptive ABCAgent-based modelsColorectal cancer

Identifiers

PMID34691351
PMCPMC8534811
OpenAlexW2795626393

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.